Winter Sports Safety
PodcastDX
Winter sports are thrilling and enjoyable, but they come with unique risks that require careful preparation and safety measures. Activities such as skiing, snowboarding, ice skating, and sledding expose participants to hazards like icy conditions, extreme cold, and potential collisions. Wearing appropriate protective gear, such as helmets, padded clothing, and eye protection, can significantly reduce the risk of injury. Additionally, dressing in moisture-wicking and layered clothing helps maintain body warmth and prevent frostbite or hypothermia. It is also crucial to stay hydrated, as...
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Vectors in a Hotter World
PodcastDX
This week we discuss vectors in a hotter world. Vector-borne diseases, which are transmitted by hematophagous arthropods such as mosquitoes, ticks, and sandflies, pose a significant burden on global public health. These diseases disproportionately affect populations in tropical and subtropical regions, where environmental conditions favor the survival and proliferation of vectors. Given that vectors are ectothermic organisms, their life cycles, reproduction, survival rates, and geographic distribution are heavily influenced by climate variables such as temperature, rainfall, and...
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Intro to Ehlers Danlos Syndrome
PodcastDX
This week we discuss the basics about a topic several of our guests have spoken about- Ehlers Danlos Syndrome or EDS. Ehlers-Danlos syndrome is a group of inherited disorders that affect your connective tissues — primarily your skin, joints and blood vessel walls. Connective tissue is a complex mixture of proteins and other substances that provide strength and elasticity to the underlying structures in your body. The Ehlers-Danlos syndromes received and this is what we now know: EDS are heritable connective tissue disorders affecting the quality of collagen in every...
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Food Is Medicine
PodcastDX
This week we discuss "Food is Medicine". The concept of "food is medicine" refers to the idea that certain foods and dietary patterns can play a significant role in promoting health, preventing disease, and managing chronic conditions. This concept is based on the notion that food is not only a source of energy and nutrients but also a powerful tool for influencing our physiological and biochemical processes. Access to affordable, nutritious food is crucial for good health, yet many Americans, particularly in under-resourced communities, face barriers. The result? A...
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Too Fast, Too Slow, Just Right Heart Rhythms
PodcastDX
Our guest today is Evelyn Gamble. Evelyn is a dedicated healthcare worker and passionate heart disease advocate. With a deep commitment to improving health outcomes, Evelyn uses her personal and professional experiences to raise awareness about heart health, particularly for young adults. As a strong voice for change, she aims to inspire others to take proactive steps in managing their heart health and to advocate for better care and resources for those affected by heart disease. Definition: A heart arrhythmia, also known as a cardiac arrhythmia, is an abnormal rhythm...
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Tuberculosis Resurgence
PodcastDX
This week's episode we will discuss the resurgence of TB/ Tuberculosis. TB is a treatable and curable disease. Active, drug-susceptible TB disease is treated with a standard 6-month course of 4 antimicrobial drugs that are provided with information and support to the patient by a health worker or trained volunteer. Without such support, treatment adherence is more difficult. Since 2000, an estimated 66 million lives were saved through TB diagnosis and treatment. A total of 1.5 million people died from TB in 2020 (including 214 000 people with HIV). Worldwide, TB is the 13th leading...
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Virtual Sciatica Therapy
PodcastDX
Our guest today is a Physical Therapist that specializes in Sciatica. Dean Volk, MPT, and owner of Sciatica Relief Now, has spent over 33 years revolutionizing sciatica treatment. After owning three successful clinics and a cash concierge practice and working with professional athletes, Volk transitioned to a virtual model in 2018, turning this side hustle into a full-time operation in 2021. Now based in Santa Monica, CA, Dean and his team of coaches provide virtual consultations and coaching to clients worldwide, helping them live their lives to the fullest. The cornerstone of Sciatica...
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Myasthenia Gravis with Tasha White
PodcastDX
In this episode we will discuss Myasthenia Gravis, an Autoimmune Disease affecting the neuromuscular system of the body with Tasha White, Director of a new Non-profit organization called My Walk with MG located in St. Louis, MO. Myasthenia gravis is a chronic neuromuscular disease that causes weakness in the voluntary muscles. Voluntary muscles include muscles that connect to a person’s bones, muscles in the face, throat, and diaphragm. They contract to move the arms and legs and are essential for breathing, swallowing and facial movements. Myasthenia gravis is an autoimmune...
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Blood Clots
PodcastDX
This week we discuss blood clots A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Clotting is a necessary process that can excessive blood loss when you have a cut, for example. Thrombosis is when a blood clot and reduces blood flow. There are two types: Arterial thrombosis occurs when a blood clot forms in an artery. Venous thrombosis occurs when a blood clot forms in a vein. When a clot forms inside one of your veins, it may dissolve on its own. However, sometimes a clot doesn’t dissolve on its own, or part of it...
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Hearing Loss
PodcastDX
This week we discuss hearing loss. A person who is not able to hear as well as someone with normal hearing – hearing thresholds of 20 dB or better in both ears – is said to have hearing loss. Hearing loss may be mild, moderate, severe or profound. It can affect one ear or both ears and leads to difficulty in hearing conversational speech or loud sounds. Hard of hearing refers to people with hearing loss ranging from mild to severe. People who are hard of hearing usually communicate through spoken language and can benefit from hearing aids, cochlear implants, and other assistive devices as...
info_outlineThis week we will discuss M-RNA vaccines. Our guest is Thomas VanCott, PhD. Thomas VanCott is currently the Chief Scientific Officer for Combined Therapeutics, a Boston based biotech company developing targeted mRNA therapies. Prior to this he served as the Chief Technology and Strategy Officer for Catalent Cell & Gene Therapy, a global CDMO manufacturing viral vectors for gene and cell therapies as wells as plasmid DNA & mRNA platforms based in Baltimore, MD. He was responsible for strategically enhancing CMC services to meet the market demand of increasingly complex gene and cell therapy products as well as leading the product development and internal R&D teams. Prior to this, he was the CEO for 10 years at a Maryland-based CMO/CRO (ABL) where he was responsible for the strategic international growth of the company. He has been involved in biologics product development for over 25 years. He has a PhD in physical chemistry and started his career as a Captain in the US Army stationed at Walter Reed Army Institute of Research (WRAIR) studying and developing HIV vaccines for international deployment from initial construction through preclinical development, GMP manufacturing and clinical development.
Vaccines help prevent infection by preparing the body to fight foreign invaders (such as bacteria, viruses, or other pathogens). All vaccines introduce into the body a harmless piece of a particular bacteria or virus, triggering an immune response. Most vaccines contain a weakened or dead bacteria or virus. However, scientists have developed a new type of vaccine that uses a molecule called messenger RNA (mRNA) rather than part of an actual bacteria or virus. Messenger RNA is a type of RNA that is necessary for protein production. Once cells finish making a protein, they quickly break down the mRNA. mRNA from vaccines does not enter the nucleus and does not alter DNA.
mRNA vaccines work by introducing a piece of mRNA that corresponds to a viral protein, usually a small piece of a protein found on the virus’s outer membrane. (Individuals who get an mRNA vaccine are not exposed to the virus, nor can they become infected with the virus by the vaccine.) By using this mRNA, cells can produce the viral protein. As part of a normal immune response, the immune system recognizes that the protein is foreign and produces specialized proteins called antibodies. Antibodies help protect the body against infection by recognizing individual viruses or other pathogens, attaching to them, and marking the pathogens for destruction. Once produced, antibodies remain in the body, even after the body has rid itself of the pathogen, so that the immune system can quickly respond if exposed again. If a person is exposed to a virus after receiving mRNA vaccination for it, antibodies can quickly recognize it, attach to it, and mark it for destruction before it can cause serious illness.
Like all vaccines in the United States, mRNA vaccines require authorization or approval from the Food and Drug Administration (FDA) before they can be used. Currently vaccines for COVID-19, the disease caused by the SARS-CoV-2 coronavirus, are the only authorized or approved mRNA vaccines. These vaccines use mRNA that directs cells to produce copies of a protein on the outside of the coronavirus known as the “spike protein”. Researchers are studying how mRNA might be used to develop vaccines for additional diseases. (credits: Medline Plus)