Whooping Cough or Pertussis
PodcastDX
Whooping cough, also known as pertussis, is a highly contagious respiratory infection caused by the bacteria Bordetella pertussis. It's characterized by severe, persistent coughing fits, often ending with a high-pitched "whoop" sound. The disease can be very serious, especially for infants, and is preventable through vaccination. Whooping cough is an illness that can spread easily. It's also called pertussis. An infection with bacteria causes it. Many people with the illness get a serious hacking cough. Breathing in after coughing often causes a high-pitched noise that sounds like a...
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Summer Health and Safety
PodcastDX
What’s your plan for this summer? Enjoying the water? Going camping? Firing up the grill? Whatever you prefer, we have safety steps to follow. And don’t forget your furry friends. There are steps you can take to help keep them safe too. Skin safety Children's skin is more susceptible to sunburns and UV damage from the sun than adults. Before going outside, and dress your kids in protective clothing like rash guards and hats. Choose a sunscreen with a minimum SPF of 30 with broad-spectrum protection that blocks both UVA and UVB rays. Sunscreen is only safe for children over 6 months...
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Hepatitis (Re-Run)
PodcastDX
Hepatitis means inflammation of the liver. The liver is a vital organ that processes nutrients, filters the blood, and fights infections. When the liver is inflamed or damaged, its function can be affected. Heavy alcohol use, toxins, some medications, and certain medical conditions can cause hepatitis. However, hepatitis is often caused by a virus. In the United States, the most common types of viral hepatitis are , , and . Hepatitis D, also known as “delta hepatitis,” is a liver infection caused by the hepatitis D virus (HDV). Hepatitis D only occurs in people who are also...
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Narcolepsy (rerun)
PodcastDX
Narcolepsy is a chronic sleep disorder characterized by overwhelming daytime drowsiness and sudden attacks of sleep. People with narcolepsy often find it difficult to stay awake for long periods of time, regardless of the circumstances. Narcolepsy can cause serious disruptions in your daily routine. Our guest today is Lindsey who will discuss her life with narcolepsy. Lindsey grew up in Charlotte NC and is currently residing nearby in Belmont, NC with her husband and dog. She was diagnosed in May of 2019 after dealing with symptoms since childhood. She was previously...
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Migraine
PodcastDX
On today's show we are speaking once again with Sheila Ames. As you may recall, Sheila is a Registered Nurse and the founder of "Ames Alchemy Coaching" which can be found on Facebook and Instagram. Today she joins us to discus her life-long struggles with migraines. A migraine is a headache that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head. It's often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. Migraine attacks can last for hours to days, and the pain can be so severe that it interferes with...
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Strep
PodcastDX
Bacteria called group B Streptococcus (group B strep, GBS) commonly live in people’s gastrointestinal and genital tracts. The gastrointestinal tract is the part of the body that digests food and includes the stomach and intestines. The genital tract is the part of the body involved in reproduction and includes the vagina in women. Most of the time the bacteria are not harmful and do not make people feel sick or have any symptoms. Sometimes the bacteria invade the body and cause certain infections, which are known as GBS disease. GBS bacteria can cause many types of infections: ...
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Incontinence
PodcastDX
Incontinence refers to the involuntary leakage of urine (urinary incontinence) or feces (bowel incontinence), a common problem that can significantly impact quality of life. Urinary Incontinence: Definition: Urinary incontinence is the accidental loss of urine. Types: Stress incontinence: Leakage during physical activity or when the bladder is under pressure (coughing, sneezing, laughing). Urge incontinence: A strong, sudden urge to urinate that you can't control, leading to leakage. ...
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Winter Sports Safety
PodcastDX
Winter sports are thrilling and enjoyable, but they come with unique risks that require careful preparation and safety measures. Activities such as skiing, snowboarding, ice skating, and sledding expose participants to hazards like icy conditions, extreme cold, and potential collisions. Wearing appropriate protective gear, such as helmets, padded clothing, and eye protection, can significantly reduce the risk of injury. Additionally, dressing in moisture-wicking and layered clothing helps maintain body warmth and prevent frostbite or hypothermia. It is also crucial to stay hydrated, as...
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Vectors in a Hotter World
PodcastDX
This week we discuss vectors in a hotter world. Vector-borne diseases, which are transmitted by hematophagous arthropods such as mosquitoes, ticks, and sandflies, pose a significant burden on global public health. These diseases disproportionately affect populations in tropical and subtropical regions, where environmental conditions favor the survival and proliferation of vectors. Given that vectors are ectothermic organisms, their life cycles, reproduction, survival rates, and geographic distribution are heavily influenced by climate variables such as temperature, rainfall, and...
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Intro to Ehlers Danlos Syndrome
PodcastDX
This week we discuss the basics about a topic several of our guests have spoken about- Ehlers Danlos Syndrome or EDS. Ehlers-Danlos syndrome is a group of inherited disorders that affect your connective tissues — primarily your skin, joints and blood vessel walls. Connective tissue is a complex mixture of proteins and other substances that provide strength and elasticity to the underlying structures in your body. The Ehlers-Danlos syndromes received and this is what we now know: EDS are heritable connective tissue disorders affecting the quality of collagen in every...
info_outlineThis week we will discuss M-RNA vaccines. Our guest is Thomas VanCott, PhD. Thomas VanCott is currently the Chief Scientific Officer for Combined Therapeutics, a Boston based biotech company developing targeted mRNA therapies. Prior to this he served as the Chief Technology and Strategy Officer for Catalent Cell & Gene Therapy, a global CDMO manufacturing viral vectors for gene and cell therapies as wells as plasmid DNA & mRNA platforms based in Baltimore, MD. He was responsible for strategically enhancing CMC services to meet the market demand of increasingly complex gene and cell therapy products as well as leading the product development and internal R&D teams. Prior to this, he was the CEO for 10 years at a Maryland-based CMO/CRO (ABL) where he was responsible for the strategic international growth of the company. He has been involved in biologics product development for over 25 years. He has a PhD in physical chemistry and started his career as a Captain in the US Army stationed at Walter Reed Army Institute of Research (WRAIR) studying and developing HIV vaccines for international deployment from initial construction through preclinical development, GMP manufacturing and clinical development.
Vaccines help prevent infection by preparing the body to fight foreign invaders (such as bacteria, viruses, or other pathogens). All vaccines introduce into the body a harmless piece of a particular bacteria or virus, triggering an immune response. Most vaccines contain a weakened or dead bacteria or virus. However, scientists have developed a new type of vaccine that uses a molecule called messenger RNA (mRNA) rather than part of an actual bacteria or virus. Messenger RNA is a type of RNA that is necessary for protein production. Once cells finish making a protein, they quickly break down the mRNA. mRNA from vaccines does not enter the nucleus and does not alter DNA.
mRNA vaccines work by introducing a piece of mRNA that corresponds to a viral protein, usually a small piece of a protein found on the virus’s outer membrane. (Individuals who get an mRNA vaccine are not exposed to the virus, nor can they become infected with the virus by the vaccine.) By using this mRNA, cells can produce the viral protein. As part of a normal immune response, the immune system recognizes that the protein is foreign and produces specialized proteins called antibodies. Antibodies help protect the body against infection by recognizing individual viruses or other pathogens, attaching to them, and marking the pathogens for destruction. Once produced, antibodies remain in the body, even after the body has rid itself of the pathogen, so that the immune system can quickly respond if exposed again. If a person is exposed to a virus after receiving mRNA vaccination for it, antibodies can quickly recognize it, attach to it, and mark it for destruction before it can cause serious illness.
Like all vaccines in the United States, mRNA vaccines require authorization or approval from the Food and Drug Administration (FDA) before they can be used. Currently vaccines for COVID-19, the disease caused by the SARS-CoV-2 coronavirus, are the only authorized or approved mRNA vaccines. These vaccines use mRNA that directs cells to produce copies of a protein on the outside of the coronavirus known as the “spike protein”. Researchers are studying how mRNA might be used to develop vaccines for additional diseases. (credits: Medline Plus)