471 Biofilms, Biocides, and TTPC: A Deep Dive with Dr. Jeff Kramer
Release Date: 04/10/2026
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info_outlineBiofilm is not a fringe issue in cooling systems. As Dr. Jeff Kramer explains, it is a given. That matters because biofilm affects heat transfer, contributes to corrosion, and can serve as a reservoir for Legionella in treated systems. In this conversation, Trace Blackmore and Dr. Kramer examine what experienced water treaters should be looking for when choosing and evaluating a microbiological control program.

Biofilm as an operating problem
Dr. Jeff defines biofilm as a community of microorganisms attached to a surface and held together by an external polymeric matrix. From there, the discussion moves quickly into why these matter in the field. He points to research showing that biofilms can be more insulating than mineral scale, then explains how microbial activity and patchy film formation can intensify corrosion risk. He also notes that Legionella can be harbored within biofilm, making clean-looking bulk water an incomplete picture of system condition.
Choosing the right biocide program

A strong oxidizing biocide foundation remains central, whether based on chlorine or bromine. However, Dr. Jeff makes a practical distinction that matters to service professionals: some non-oxidizing biocides kill biofilm organisms without removing the film, while others both kill and remove. He also explains why shock dosing often outperforms smaller, more frequent additions, and why biocide timing should be evaluated in the context of oxidizer compatibility, halogen demand, and actual system feedback rather than habit or opinion.
Surfactants, TTPC, and field realities
The conversation also covers how surfactants and quaternary compounds can disrupt microbial membranes and improve biocide penetration. Dr. Jeff shares lab and field insight on TTPC, including its strong performance in kill-and-removal testing and its known interference with PTSA fluorescence programs. The discussion closes with practical monitoring advice: inspect the basin, feel below the waterline, trend dip slides, watch approach temperatures, and pay attention to residence time when selecting products for different system volumes and turnover rates.
Better microbiological control is not about one product or one rule of thumb. It is about understanding the system, interpreting feedback, and matching chemistry to operating reality so performance can be maintained over time.
Listen to the full conversation above. Explore related episodes below. Stay engaged, keep learning, and continue scaling up your knowledge!
Quotes
“You need to understand; listen to the feedback you're getting from the system and then adjust your program appropriately. “
“Don’t be afraid to ask for help because you don't know you don't know everything “
Phone: (404)-386-0518
Email: jkramer@mfgchemical.com
Website: https://www.radicalpolymers.com/
LinkedIn: Jeff Kramer | LinkedIn
Guest Resources Mentioned
CTI’s New Biocide Options For Biofouling Control by Jeffrey Kramer
Scaling UP! H2O Resources Mentioned
Scaling UP! H2O Academy video courses
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