SPOS #1000 – Patrick Tanguay On Paths To Better Thinking
Release Date: 09/07/2025
SPOS #1000 – Patrick Tanguay On Paths To Better Thinking
Thinking With Mitch Joel
Welcome to episode #1000 of Six Pixels of Separation - The ThinkersOne Podcast. is a self-described generalist, synthesist and curator whose lifelong curiosity and love of reading have led him across multiple careers, and now shape one of the most thoughtful newsletters in the futures-thinking space. As the creator of , a weekly “futures thinking observatory” (and one of my most favorite reads), Patrick spotlights signals of change across technology, society, and culture. He helps readers trace emergent paths instead of prescribing them. Alongside his writing, he designed and launched...
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SPOS #999 – Noah Giansiracusa On The Algorithms That Run Your Life
Thinking With Mitch Joel
Welcome to episode #999 of Six Pixels of Separation - The ThinkersOne Podcast. is an associate professor of mathematics at and a visiting scholar at who has built a reputation for translating the hidden power of algorithms into plain language that empowers individuals. With a PhD in algebraic geometry from Brown, he’s always bringing a mathematician’s eye to the cultural and social impact of technology. His earlier book, , was praised by Nobel Prize–winning economist as “the best guide to the strategies and stakes of this battle for the future.” In his latest book, , Noah shows...
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SPOS #998 – Annie Wilson On The Growth Dilemma
Thinking With Mitch Joel
Welcome to episode #998 of Six Pixels of Separation - The ThinkersOne Podcast. is a marketing professor at the and co-author, with , of . Her work examines the deep interplay between consumer behavior, culture and brand identity, helping leaders understand why growth often creates as many risks as it does opportunities. In The Growth Dilemma, Annie unpacks how efforts to reach new customer segments can clash with the values of loyal buyers, sometimes threatening the very meaning of a brand. Drawing from real-world examples (from ’s software missteps to ’s unintended association with...
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SPOS #997 – Adam Brotman On Being AI First
Thinking With Mitch Joel
Welcome to episode #997 of Six Pixels of Separation - The ThinkersOne Podcast. What happens when nearly everything a marketer or strategist does today becomes instant, automatic… and nearly free? That’s the premise of , the new book from (my guest this week) and his co-author , which confronts the existential shift that AI is bringing to brand strategy, customer experience and creative work. Adam, the former Chief Digital Officer at and co-founder of the strategic consultancy , brings firsthand experience building digital platforms that changed how global businesses operate. In this...
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SPOS #996 – Christie Smith On Distributed Teams, Generative AI And Global Shifts
Thinking With Mitch Joel
Welcome to episode #996 of Six Pixels of Separation - The ThinkersOne Podcast. is a former senior executive at , and with over three decades of leadership experience across industries including life sciences, consumer goods and finance. She holds a doctorate in Social Work and Organizational Psychology and now leads , a leadership advisory firm focused on redefining the future of work. In her new book, (along with her co-author ), Christie outlines a bold new framework for leaders navigating a post-pandemic, AI-driven, decentralized world. This episode explores the urgent need for...
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SPOS #995 – Nelson Repenning On Delivering Real Results At Work
Thinking With Mitch Joel
Welcome to episode #995 of Six Pixels of Separation - The ThinkersOne Podcast. has built his career at and by asking a simple but haunting question: why do so many smart, capable organizations fail to get the right work done? In his new book, , Nelson (along with his co-author, ) introduces dynamic work design: a practical framework that helps leaders move beyond broken systems and toward better execution. In this conversation, we explore the five principles behind this approach: solving the right problem, structuring for discovery, connecting the human chain, regulating for flow and...
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SPOS #994 – Vicki Tan On Life's Big And Little Decisions
Thinking With Mitch Joel
Welcome to episode #994 of Six Pixels of Separation - The ThinkersOne Podcast. has designed experiences for some of the most influential companies in the world (, , , , ) and her work has always focused on helping people make better choices in complex environments. Her new book, , continues that mission in a radically creative form. This isn’t your typical self-help guide. It’s an interactive journey through the beautiful mess of human decision-making, shaped by the science of cognitive bias, the power of storytelling and the playfulness of visual design. Vicki explores how our mental...
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SPOS #993 – Angela Chee On The Power Of Only
Thinking With Mitch Joel
Welcome to episode #993 of Six Pixels of Separation - The ThinkersOne Podcast. is a keynote speaker, media and communication coach, and author of , a book that challenges us to rethink the spaces we occupy and the voices we often silence… especially our own. In this conversation, Angela explores what it means to truly “own your voice” in an era defined by visibility and vulnerability, noise and nuance. Angela speaks candidly about how being the “only” in the room (whether because of race, gender, background, or perspective) is not a disadvantage but a profound source of power and...
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SPOS #992 – Dave Whorton On Building Companies That Last
Thinking With Mitch Joel
Welcome to episode #992 of Six Pixels of Separation - The ThinkersOne Podcast. has spent his career building, backing and reimagining companies, but not in the way Silicon Valley usually does it. As founder of and author of (which he co-authored with ), Dave champions a different breed of business: evergreen companies. These are organizations designed to last generations, rooted in purpose, resilience and profitability… not just hypergrowth and exit strategies. Before this pivot, Dave had a front-row seat to the “get-big-fast” movement as an associate partner at , and he co-founded...
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SPOS #991 – Bob Goodson On The "Like" Button (And How It Changed The World)
Thinking With Mitch Joel
Welcome to episode #991 of Six Pixels of Separation - The ThinkersOne Podcast. is President and Founder of , an AI-driven company whose models are used by a third of the Fortune 50. Before launching Quid, he was the first employee at , where he witnessed (and helped shape) the birth of the like button. Bob’s academic roots in language theory () and his deep curiosity about patterns of innovation led him to co-author , an illuminating book about how a simple social media feature rewired global communication and commerce. In this episode, we dig into the origin story of the like button and...
info_outlineWelcome to episode #1000 of Six Pixels of Separation - The ThinkersOne Podcast.
Patrick Tanguay is a self-described generalist, synthesist and curator whose lifelong curiosity and love of reading have led him across multiple careers, and now shape one of the most thoughtful newsletters in the futures-thinking space. As the creator of Sentiers, a weekly “futures thinking observatory” (and one of my most favorite reads), Patrick spotlights signals of change across technology, society, and culture. He helps readers trace emergent paths instead of prescribing them. Alongside his writing, he designed and launched Station C, one of the first co-working spaces, co-founded the print magazine, The Alpine Review, and seeded communities like Creative Mornings and some of the earlier community get-togethers for the digital enthusiasts. For episode #1000, Patrick guides us through how he curates global currents of change, explores how platform design, sense-making systems and personal knowledge management influence our capacity to understand the future, and why the skills of generalists matter now more than ever. He walks us through why Sentiers became such a respected newsletter and how its architecture reinforces and expands his handwritten trail of ideas. Across the show we consider how to build a personal “observatory,” not just follow feed algorithms, how to connect seemingly disparate signals from AI to city futures, and why being able to notice what’s happening before everyone else is becoming more crucial... and more rare. This is an episode for curious minds, digital gardeners and anyone searching for clarity amid chaos. I hope that you will also take a couple of moments to listen to my opening monologue about my reflections on the past 1000 episodes (nearly 20 years), and what the future will hold for this show starting next week. Enjoy the conversation…
- Running time: 1:28:08.
- Hello from beautiful Montreal.
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- Here is my conversation with Patrick Tanguay.
- Sentiers.
- The Alpine Review.
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Chapters:
(00:00) - The Evolution of Six Pixels of Separation.
(04:14) - Introducing Patrick Tanguay.
(05:31) - The Art of Thinking and Curating.
(20:56) - Foresight and Future Thinking.
(29:54) - Navigating the World of AI.
(41:41) - The Role of Reading in Deep Thinking.
(01:00:08) - The Future of Knowledge Work.
(01:10:04) - The Intersection of AI and Human Purpose.