Tech Talks Daily
What if the chemistry created by neurological disease could help activate medicine precisely where it is needed? In this episode of Tech Talks Daily, I speak with Sara Isbell, neuroscientist and co-founder of Enabled Therapeutics, about a proposed approach to one of medicine’s most stubborn problems: delivering effective drugs to diseased brain tissue without exposing healthy areas to the same activity. Sara explains how the blood-brain barrier prevents many promising compounds from reaching the brain. When drugs do enter, they may spread across healthy and diseased regions alike, creating a...
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Could the real reason enterprise AI projects remain stuck in pilot mode be hidden inside the company’s unstructured data? In this episode of Tech Talks Daily, I welcome back Oded Nagel, CEO of CTERA. We discuss why enterprise AI success depends on the condition, location, permissions, and business value of the data sitting underneath models and agents. Oded defines AI-ready data as information that is searchable, classified, and permission-aware. Many enterprises have petabytes of files distributed across offices, edge locations, legacy network-attached storage, and cloud platforms. Before...
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What happens to the value of human judgment when AI makes execution faster, cheaper, and available to almost everyone? In this episode of Tech Talks Daily, I speak with Eric Wang, Vice President of Product and AI at QuillBot. Eric has worked in artificial intelligence since 2006, with previous leadership roles at Turnitin and Chegg. He now works on AI products used by millions of people to develop ideas, improve their writing, conduct research, and create new forms of content. Eric argues that AI’s workplace impact extends far beyond automation. These tools are changing how people develop an...
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Has enterprise AI finally reached the point where impressive demonstrations are no longer enough? In this episode of Tech Talks Daily, I speak with Bruce McMahon, Chief Product Officer at CallMiner, about what he describes as the industrialization of AI: the move from experimentation and excitement toward repeatable processes, measurable ROI, better customer experiences, and technology that can operate reliably at enterprise scale. Bruce explains why business leaders are increasingly asking a much simpler question about AI: how is this going to create value? Drawing on CallMiner's experience...
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What happens when an AI agent is compromised, manipulated, or simply does something nobody expected, but already has permission to access your most sensitive systems? In this episode of Tech Talks Daily, I speak with Geoffrey Mattson, CEO of SecureAuth, about why securing enterprise AI requires businesses to think beyond protecting models and start paying much closer attention to identity, authorization, access control, and what AI agents are actually allowed to do. Geoffrey argues that AI agents present a different security challenge from traditional software. Conventional applications can be...
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Companies are spending billions on GPUs, data centers, foundation models, and AI infrastructure. But what happens when the network connecting all of it cannot keep up? In this episode of Tech Talks Daily, I welcome back Avi Freedman, co-founder and CEO of Kentik, five years after our previous conversation. Avi has been operating large-scale networks since the 1990s, including more than a decade at Akamai, and brings a rare combination of founder experience and hands-on knowledge of how the internet actually works. We discuss why network performance is becoming an important factor in...
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Is AI really causing widespread job losses, or are a small number of announcements creating a much larger narrative? In this episode of Tech Talks Daily, I speak with Marvin Pohl, chief data scientist and cofounder of Clarecast, about AI layoffs, quiet restructuring, predictive workforce intelligence, and the responsibility that comes with forecasting company growth. Marvin’s career began in physics and physical chemistry. After completing his PhD in Germany, he worked at Berkeley Lab and UC Berkeley before moving into data science at BASF. He describes how his role changed as generative AI...
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What happens when an AI agent is authorized to make a payment, but nobody can verify the wider agreement behind it? In this episode of Tech Talks Daily, I speak with Zor Gorelov of Blue Language Labs about the infrastructure businesses may need as AI agents move from answering questions to negotiating, approving, purchasing, coordinating, and settling commercial activity. Many current business processes depend on human coordination. People reconcile spreadsheets, chase signatures, confirm deliveries, review exceptions, and resolve disagreements between systems. This work often remains...
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What separates an embedded finance partnership that changes customer behavior from an integration nobody would miss? In this episode of Tech Talks Daily, I speak with Rory Herriman, Chief Technology Officer and Chief Operations Officer for Zip’s US business. Rory works across product, technology, operations, and business strategy, giving him a broad view of what happens after the API connection is complete and real customers begin using the service. Rory challenges a common understanding of embedded finance as placing one financial product inside another company’s experience. Customers...
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What happens to creator loyalty when somebody delivers the work, attracts an audience, and then waits weeks to be paid? In this episode of Tech Talks Daily, I speak with Rob Israch, President at Tipalti, about the payment infrastructure supporting the creator economy. Platforms may be able to add thousands of creators quickly, but the systems behind onboarding, tax collection, approvals, global payouts, communication, and reconciliation often struggle to keep pace. Rob cites research suggesting 87 percent of creators have experienced late payments. For a creator, payment is a direct test of...
info_outlineWhy do so many enterprise AI initiatives begin with impressive demonstrations but struggle to produce measurable business value?
In this episode of Tech Talks Daily, I speak with Dom Selvon, CTO and value partner at Valliance, about enterprise AI ROI, outcome-based consulting, build versus buy decisions, proprietary data, ontologies, and governance.
Valliance is an AI-native consultancy that charges against client outcomes rather than hours worked. Dom explains why his “value partner” title is deliberate. The company begins by identifying the financial or operational result a client wants and connects its own compensation with achieving that result.
Dom argues that many AI initiatives begin without a clear definition of success. The pressure to adopt AI is real, but companies frequently select technology before agreeing on the business problem, desired outcome, or measurement.
He identifies three recurring mistakes. The first is framing the project around AI rather than the business need. The second is failing to establish a metric and baseline before work begins. The third is using a consulting model that rewards billable time without connecting payment to the client’s result.
We also discuss how generative AI is changing traditional build versus buy decisions. Companies historically bought software because custom development was slow, expensive, and difficult to maintain. Coding agents can now reduce the time and cost required to create software for specific internal needs.
Dom does not believe SaaS will simply disappear. However, vendors selling convenience, workflow wrappers, or integration glue face new competition from customers who can create similar capabilities themselves. He argues that stronger SaaS positions will depend on assets a model cannot easily regenerate, including proprietary data, networks, regulatory standing, and deep workflow adoption.
This leads to a wider discussion about competitive advantage. When companies have access to similar models, generated code begins to converge. Dom believes lasting differentiation comes from company data, institutional knowledge, connected systems, employee experience, and the semantic context surrounding that information.
Dom explains why ontologies matter to enterprise AI. Raw data tells an agent what is stored in a particular field. An ontology describes the customers, orders, contracts, payments, relationships, and business rules represented by that data. This context allows people and agents to reason about information in a way that reflects how the company actually works.
Governance also needs to be designed from the beginning. Dom argues that security, permissions, accountability, and compliance allow successful pilots to expand without forcing the business to rebuild everything later.
How can leaders tell when AI is genuinely being adopted? Dom offers a surprisingly simple signal: people stop talking about AI. The technology becomes part of ordinary Monday morning work, and employees focus on completing the task rather than explaining the tool.
Has your company defined the business result, measurement, proprietary context, and governance required to turn AI enthusiasm into operational value? Listen to the episode and share your thoughts with me.