Why High-Dose Biotin Could be the Answer for Your Blood Sugar, Brains, and Beauty
Release Date: 10/18/2023
Mastering Nutrition
You could be one metabolic bottleneck away from feeling amazing. Mitome is the first at-home test that measures your cellular energy directly and gives you a personalized roadmap to optimize energy, slow aging, and protect against disease. Find it at mito.me This is not medical advice and is for educational purposes only. Chris Masterjohn, PhD, is the Founder and Scientific Director of the .
info_outlineMastering Nutrition
Aging is best explained by declining mitochondrial function over time. This answers its own “why.” Mitochondria produce the energy needed for repair so if any of it gets lost it sets up a vicious cycle. And some *always* gets lost. But how much is under your control. From Joe Rogan Experience JRE 2420. It’s a vicious cycle initiated by the second law of thermodynamics which requires a constant input of energy to prevent the collapse of order. Hence, there will always be slippage, but how much slippage depends on...
info_outlineMastering Nutrition
This is a clip from Joe Rogan Experience JRE 2420. Watch the full interview here: Chris Masterjohn, PhD, is the Founder and Scientific Director of the .
info_outlineMastering Nutrition
This is a clip from Joe Rogan Experience JRE 2420. Watch the full interview here: https://www.youtube.com/watch?v=QBn54YNnKD0
info_outlineMastering Nutrition
This is a clip from Joe Rogan Experience Episode 2420. You can watch the full interview here: https://www.youtube.com/watch?v=QBn54YNnKD0
info_outlineMastering Nutrition
Mitochondria govern everything. Watch this with the slides here: https://www.youtube.com/watch?v=mED1_L3wZbc Mitochondria convert your food to usable energy in the form of ATP, which is used to produce, maintain, repair, distribute, and organize everything in your body. Abundant health right now, and preserving your health throughout the lifespan toward your longevity, all depends on your mitochondria. In fact the best explanation for aging is that its a vicious cycle of declining mitochondrial function. We should always be thinking of mitochondria first. SSRIs, acne treatments, and statins...
info_outlineMastering Nutrition
Chris Masterjohn, PhD, Founder and Scientific Director of mito.me, explains why SSRI withdrawal is mitochondrial dysfunction and what to do about it. This is not medical advice, diagnosis, or treatment. 29 million Americans and about 5-10% of the world's population are on SSRIs, which have become the first-line treatment of depression. These can cause sexual dysfunction and emotional blunting in up to half of people, an unclear incidence of sleep disruption, and a rare risk of suicidality, self-harm, and new-onset psychosis. On the other hand, 20-50% of people who go off experience SSRI...
info_outlineMastering Nutrition
For a long time, most people believed that when we exercise, our muscles make lactic acid, this acidifies the muscles, and the acidity contributes to contractile failure, fatigue, and delayed-onset muscle soreness. Some people still believe this. You may have heard the argument against it from well-known figures like Andy Galpin, or, if you’re deep into the science, you may have read the work of George Brooks. In this lesson, we are going to cover the biochemistry of lactate production. We will see that we never make lactic acid, ever. We make lactate. Making lactate is fundamentally...
info_outlineMastering Nutrition
D-lactate is commonly stated to be exclusively a microbial metabolite. This is found in assumptions within the medical literature for decades even when it was long-known to be false. While D-lactate is indeed made by bacteria, D-lactate is also inarguably and irrefutably produced by human enzymes. In this podcast, moreover, I will argue the following: Microbial contribution to D-lactate in humans under normal circumstances is negligible. I coin the term “the D-lactate shuttle” to describe a role for D-lactate that should eventually make its way into biochemistry textbooks...
info_outlineMastering Nutrition
In this podcast we cover elevated creatinine, insomnia, cramps constipation, water retention, hair loss, irritation and anger, lightheadedness during lifting, bloating, aggravation of restless leg syndrome, irritation of asthma, bloody noses, anxiety, headaches, heart palpitations, twitching, and fast or slow heartbeat. The full podcast and article can be found here: Chris Masterjohn, PhD, is the Founder and Scientific Director of the .
info_outlineThe use of high-dose biotin supplements has increased almost 30-fold over the last twenty years for such problems as diabetes, smell and taste disorders, disorders of the hair, skin, and nails, and multiple sclerosis.
Studies show it can improve diabetes, and case reports show it can miraculously recover lost smell and taste even when smell and taste were lost as a result of surgery or the side effects of medications or other supplements.
Yet, some studies show multiple sclerosis gets worse on high-dose biotin. I personally developed clumsiness, short-term memory loss, and a short temper on high-dose biotin.
Some studies show it makes blood sugar get better, yet it made my blood sugar get worse.
High-dose biotin can also cause wide-ranging errors in lab tests with the potential to mask recent heart attacks, pregnancies, or allergies; to misdiagnose thyroid conditions; to give false signals about the presence or progression of tumors; to falsely raise vitamin D, B12, and folate levels; to falsely alter many hormone levels; to generate false positives for HIV and hepatitis; and to lead to unnecessary surgery and possibly even death as a result of diagnostic errors.
Most people need more biotin than they get.
Some one in 30 people need high-dose biotin for genetic reasons, and most other people should be getting lower doses.
So, how do we know how much we need, and whether we are getting the right amount? When is the right time to break open the bottle of the ten-milligram capsules?
This article covers the safety and efficacy of high-dose biotin for all the conditions documented in the literature, its potential anti-fertility effects, and how and when to balance it with other vitamins.
This podcast is a preview of a podcast reserved for Masterpass members.
Get permanent access to the video and podcast, and get the written and fully referenced article, here:
https://chrismasterjohnphd.substack.com/p/when-high-dose-biotin-is-truly-needed
Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.