You Can’t Lead the Next Generation If You’re Not Around For It — Dr. Mark Su on Longevity
The Enlightened Family Business Podcast
Release Date: 04/20/2026
The Enlightened Family Business Podcast
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Ep. 158: You Can’t Lead the Next Generation If You’re Not Around For It — Dr. Mark Su on Longevity
In this episode of the Enlightened Family Business Podcast, host Chris Yonker sits down with Dr. Mark Su, functional and longevity medicine physician, founder of RootSeek Health and True Wellness Clinic in New England, for a wide-ranging conversation on what it actually means to take authority over your own biology. Dr. Su breaks down the three-category framework he uses in his longevity practice — age-related diseases, cellular root causes of aging, and lifestyle factors anchored by muscle health — and explains why your biologic age matters far more than your chronological one. They explore the groundbreaking science behind epigenetics, telomere health, biologic age testing, and VO2 max, and why moving just one category in your VO2 max ranking is statistically more protective than quitting smoking or eliminating heart disease. Dr. Su also tackles the overwhelm of the longevity information landscape, the critical role of self-advocacy in healthcare, the underappreciated connection between trauma, ACE scores, and chronic disease, and where AI fits — and doesn’t — in helping individuals prioritize their health. A conversation for driven family business leaders who are ready to invest in their most important asset: themselves.
Episode Chapters
· 4:40 Meet Dr. Mark Su
· 8:07 Why Longevity Is Having a Moment
· 12:03 Genetics vs. Epigenetics: How Much Authority Do You Have?
· 17:29 The Three Categories of Longevity Medicine
· 27:36 The Four Horsemen: Age-Related Diseases
· 29:00 Cellular Root Causes of Aging: Telomeres, Biologic Age, and Immunity
· 32:00 Muscle as Your Longevity Organ and the VO2 Max Breakthrough
· 35:47 Testing: What’s Available, What’s DIY, and What Requires a Doctor
· 41:44 Trauma, ACE Scores, and the Stress-Longevity Connection
· 47:38 How to Find the Right Practitioner
· 53:00 The Role of AI in Personalizing Your Health
· 57:37 Hyperbaric Chambers and Emerging Treatments
· 58:46 Resources and Farewell
Websites
· drmarksu.com
· rootseekhealth.com
· truewellnessclinic.com
· chrisyonker.com
About Dr. Mark Su
Dr. Mark Su is a functional and longevity medicine physician with over a decade of practice experience in New England. He is the founder of RootSeek Health, a virtual practice specializing in chronic inflammation and longevity medicine with no geographic boundaries, and a co-founder of True Wellness Clinic, a brick-and-mortar longevity clinic offering in-person procedural treatments including hyperbaric oxygen therapy and IV ozone. Trained at Tufts and deeply influenced by the pioneering biological age research of his wife, Dr. Jessica Su of Harvard, Dr. Mark Su brings a systems-level, root-cause approach to helping patients understand where they are biologically — and what they can actually do about it. His work bridges chronic disease, longevity science, and the belief that every person deserves a clear map for living their healthiest, fullest life.