Episode 203: The Gut-Thyroid Connection: How Your Microbiome Impacts Your Metabolism
Release Date: 07/29/2025
Thyroid Answers Podcast
In episode 206 of the Thyroid Answers Podcast, I interview Dr. Justin Marchegiani regarding his newly released book, The Thyroid Reboot. Topics covered in this episode include: Why is The Thyroid Reboot book different than others? What is driving thyroiditis and hypothyroidism? Is hypothyroidism caused by an immune system out of control or an adaptive response? The impact of stressors on driving thyroiditis and hypothyroidism Starting points for addressing hypothyroidism The role of thyroid antibodies And more... Dr. Justin Marchegiani began his medical career at the University of...
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If you're taking thyroid medication but still struggling with fatigue, brain fog, and weight gain despite "perfect" lab results, this episode will change everything. Dr. Eric Balcavage reveals why millions of thyroid patients are stuck in "Thyroid Purgatory" - where labs look optimal but symptoms persist - and introduces the groundbreaking concept of cellular hypothyroidism that explains why your cells may be rejecting the thyroid hormones you're taking. Discover why the Cell Danger Response acts like a cellular security system, blocking thyroid hormone utilization even when blood...
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In episode 205 of the Thyroid Answers Podcast, Dr. Kelly Halderman returns to discuss Thyroid labs and what your doctor might be missing. In this episode, we cover: Why TSH run by itself can be a misleading test Why both total and free hormones should be run, but often aren't Understanding T3 Uptake Reverse T3: what it is and why it is improtant Thyroid antibodies: the reality behind their presence And more... If you struggle with chronic hypothyroid symptoms despite what you have been told is appropriate or "optimized" Thyroid Hormone Replacement, you must listen to this episode. The...
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In this episode, Dr. Eric Balcavage discusses the recent announcement by the FDA to remove dessicated thyroid extracts from the market. Key Topics Covered: Why this may not be a bad thing. Alternatives to DTE Why DTE prescriptions can be a slippery slope. Why DTE prescriptions may keep you stuck in thyroid purgatory Why DTE prescription may be contributing to your hypo and hyperthyroid symptoms. And more...
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Join Dr. Eric Balcavage as he explores the critical relationship between gut health and thyroid function with registered dietitian and microbiome expert Kara Siedman. This episode dives deep into how your microbiome - the collection of bacteria, fungi, and viruses living in your gut - directly impacts thyroid physiology and overall health. Kara breaks down the complex science into actionable insights, explaining how gut dysbiosis can trigger thyroid dysfunction through inflammatory pathways, intestinal permeability, and disrupted hormone conversion. You'll discover why digestive...
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In this episode, Dr. Eric Balcavage responds to a thoughtful viewer comment that challenges key aspects of his adaptive thyroid physiology model and Cell Danger Response theory. This deep-dive discussion addresses whether his approach applies to every hypothyroidism case, clarifies the 71% improvement statistic, and explores the role of T3 therapy in thyroid treatment. Key Topics Covered: Does the Cell Danger Response theory apply to all hypothyroidism cases? Clarification of the 71% patient improvement statistic - what it really means Historical use of NDT (Natural Desiccated...
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In this episode of Thyroid Answers, Dr. Eric Balcavage sits down with functional health coach Anu Simh to explore the critical connection between gut health, thyroid function, and overall metabolism. What You'll Learn: Why normal TSH doesn't mean optimal thyroid function - and what's really happening at the cellular level How chronic stress disrupts your gut microbiome and creates a cascade of health issues The difference between homeostasis and allostatic regulation - and why understanding this changes everything Why gut protocols often fail long-term (and what's...
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Dr. Eric Balcavage interviews Nagina Abdullah about why traditional weight loss approaches fail for women with thyroid issues, especially in midlife. Nagina shares her personal journey from yo-yo dieting to losing 40 pounds using metabolism-focused strategies and reveals the framework she's used to help 1600+ women. Key Topics Covered: Why "calories in, calories out" doesn't work in midlife How perimenopause changes metabolism and increases inflammation The role of stress, sleep, and under-eating in weight gain Nagina's "Tested & Perfected Fat Burning Food...
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Join Dr. Eric Balcavage as he explores the cutting-edge world of nuclear medicine with Dr. Munir Ghesani, Chief Medical Officer at United Theranostics. Discover how theranostics—the fusion of diagnostics and therapeutics—is revolutionizing cancer treatment, particularly for thyroid conditions. Key Topics Covered: The fascinating history of nuclear medicine, born from thyroid treatment in the 1940s How radioactive iodine therapy works and why it's so effective for thyroid cancer The difference between traditional treatment and modern theranostic approaches Revolutionary redifferentiation...
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In this in-depth episode of Thyroid Shorts, Dr. Eric Balcavage addresses one of the most misunderstood aspects of thyroid physiology: T4 to T3 conversion problems. What You'll Learn: Why conventional medicine ignores conversion issues and focuses only on TSH The critical difference between "broken" physiology vs. adaptive responses How deiodinase enzymes (D1, D2, D3) actually control thyroid hormone conversion Why your body might be intentionally reducing T4 to T3 conversion The real reasons behind elevated reverse T3 levels Why T3 medication often backfires and creates more problems...
info_outline- Why normal TSH doesn't mean optimal thyroid function - and what's really happening at the cellular level
- How chronic stress disrupts your gut microbiome and creates a cascade of health issues
- The difference between homeostasis and allostatic regulation - and why understanding this changes everything
- Why gut protocols often fail long-term (and what's missing from most approaches)
- The truth about probiotics, fermented foods, and prebiotic fibers
- How ultra-processed foods damage your microbiome - and how quickly you can reverse it
- Why GLP-1 medications work but don't address root causes
- The behavioral and mindset shifts that make healing sustainable
- The mitochondria-microbiome-thyroid connection
- Why restrictive diets often backfire
- How to eat for your individual body and microbiome
- The role of nervous system regulation in gut healing
- Practical strategies for sustainable behavior change
ANU SIMH is a board-certified functional health coach and the founder of 9 Arms of Wellness. She specializes in helping busy women lose weight and maintain their goal weight by focusing on gut health. Her personalized and unique philosophy has successfully guided hundreds of women in achieving and maintaining their goals. Anu is now training other coaches in her methodology.
Based in La Jolla, California, Anu sees clients nationwide virtually. Her passion lies in the microbiome; she is also a skilled plant-based chef. Her new book, Flourish From Within, reveals the importance of gut health for overall well-being and includes over 50 plant-based recipes. Anu's guiding principle is to help people get off medications for lifestyle diseases through diet and lifestyle changes.