Lyme Insider by Dr. Tom Moorcroft

The Lyme Insider podcast, hosted by Dr. Tom Moorcroft, DO, delves into the complexities (and mysteries) of chronic Lyme disease and other tick-borne illnesses, aiming to challenge the status quo and illuminate the murky areas of medical research and clinical practice. The show commits to questioning and learning from top scientific minds, translating complex research into actionable knowledge for medical professionals and patients alike. By engaging with leading experts, the podcast seeks to refine diagnostic and treatment approaches while maintaining a commitment to scientific integrity and patient-centered care, promising listeners insightful discussions informed by science and experience.

Healing Anxiety, PANS, and Chronic Illness — The Truth No One Told You 11/13/2025

Why Doctors Are Using Psychedelics for Treatment-Resistant Lyme 10/06/2025

Why Doctors Are Using Psychedelics for Treatment-Resistant Lyme Chronic Lyme disease patients often struggle with treatment-resistant neuropsychiatric symptoms that conventional medicine can't address. In this groundbreaking conversation, discover how microdosing psilocybin is offering new hope for those stuck in rigid thought patterns, depression, anxiety, and cognitive dysfunction. Can microdosing psilocybin help people with chronic Lyme? While it doesn’t treat the infection itself, new case reports show it may ease the mental and emotional patterns that keep people stuck. Here’s one published study on psilocybin microdosing and chronic Lyme: You'll learn: ✅ How microdosing differs from recreational psychedelic use ✅ The science behind neuroplasticity and default mode network changes ✅ Why proper coaching and journaling protocols are essential ✅ Case reports showing success in treatment-resistant patients ✅ Safe dosing guidelines and harm reduction practices | ✅ How to integrate mindfulness practices for lasting results ✅ The difference between therapy and coaching approaches ✅ Why "set and setting" matter even with microdoses Seth Marcus, mindful psychedelic coach and creator of the Microdosing Journal, shares his professional approach to helping high-performers and chronic illness patients use these ancient medicines safely and effectively as tools for healing and personal growth. 🍃 Learn more about Dr. Tom's approach to Lyme Disease: 👉 📚 Learn more about Dr. Tom’s Lyme Training Program for Practitioners: 👉 📋 Connect with Seth Marcus and the Microdosing Journal: 👉 📱 Connect with Dr. Tom Moorcroft: 📷 Instagram: 🎥 Facebook: 🧑💻 LinkedIn: ⏱️ Timestamps: 00:00 - Introduction: Microdosing for chronic Lyme brain 02:25 - Meet Seth Marcus: From personal healing to professional coaching 07:04 - Key benefits: Focus, creativity, relationships, and mood 14:19 - The Microdosing Journal: Structure meets flexibility 25:17 - How psychedelics really work: Opening the heart 32:00 - Default mode network and rigid thought patterns 38:11 - Coaching vs therapy: Building your ideal future 44:07 - Why high-performers need coaches 51:23 - Safe microdosing protocols and guidelines 1:03:05 - Prayer, intention, and treating medicine as sacrament 1:14:25 - Debunking lethal dose myths 1:17:20 - Message to healthcare professionals /episode/index/show/fullcuplife/id/38485200

Why Lyme Treatments Keep Failing: The Biology of Trauma 09/23/2025

Why Lyme Treatments Keep Failing: The Biology of Trauma Are you stuck in your healing journey with Lyme disease, mold illness, long COVID, or another chronic condition? You’ve tried the protocols, supplements, and treatments—but you’re still not getting better. Why? In this powerful conversation, Dr. Tom Moorcroft sits down with Dr. Aimie Apigian, physician, trauma expert, and author of The Biology of Trauma, to explore how unresolved trauma and nervous system dysregulation keep the body stuck in protection mode—blocking true healing. You’ll learn: Why trauma biology—not just infections—may be the missing link in Lyme and chronic illness recovery. How unresolved trauma imprints on the nervous system, fueling inflammation and autoimmunity. Why willpower and “trying harder” don’t work when the body is stuck in survival. Simple, science-based steps to reset your nervous system so healing can finally happen. Whether you’re a patient struggling with chronic illness or a clinician looking for better ways to support your patients, this episode will give you a whole new perspective on what it takes to heal. 📘 Get Dr. Aimie’s book The Biology of Trauma here: ▶️ Subscribe for more conversations on Lyme, chronic illness, and healing. #LymeDisease #ChronicIllness #BiologyOfTrauma #HealingTrauma #LongCOVID #MoldIllness #DrAimieApigian #DrTomMoorcroft 🍃 Learn more with my Lyme Disease Practitioner Certification Program: 👉https://lymetraining.org 📋 Additional Resources: 🌐 Origins Of Health: 📱 Connect with me here: 📷 Instagram: 🎥 Facebook: 💻 LinkedIn: 00:00 Intro: Why trauma biology matters in Lyme 00:36 Medical gaslighting & trauma in chronic illness 01:37 Actionable, simple tools vs. theory (Dr. Aimie’s approach) 03:22 From addiction medicine to somatic exercises 04:24 60-second nervous system shifts you can do anywhere 05:24 Self-reliance: healing tools that don’t depend on a practitioner 06:00 Tracking states: the Nervous System Journal & time in safety 07:09 Micro-moments of safety & hormesis (the 20–25% rule) 08:46 Clinicians: regulate first—lead by example 10:38 Over- vs under-reacting: how stored trauma shows up 11:45 What is trauma (really)? Beyond ACE scores 13:16 Crossing the line: “too much too fast” & “too little too long” 14:59 Overwhelm vs. stress: different strategies 16:20 Step One is safety: invite the body, don’t force it 17:20 Rebuilding internal safety & restoring intuition 18:55 Worthiness, self-sabotage & Agreement #3: responsibility 20:03 Trauma as survival: a universal pattern 21:00 “The healing is in the living” — living now vs. waiting 22:48 Why she wrote the book: a manual for your nervous system 24:02 Tom’s Lyme story: 8 years sick → 13+ years symptom-free 25:01 What changed: choose life first, healing follows 26:28 If I’d had this book, I’d have healed faster /episode/index/show/fullcuplife/id/38326680

Healing Lyme: Why Killing Bugs Isn’t Enough with Dr. Myriah Hinchey 08/18/2025

Healing Lyme: Why Killing Bugs Isn’t Enough with Dr. Myriah Hinchey 🌿 Unlock the Power of Botanical Medicine for Lyme Disease & Chronic Illness | Expert Insights with Dr. Myriah Hinchey Struggling with Lyme disease or chronic infections? Discover how botanical medicine can supercharge your healing journey! In this episode of The Lyme Insider Podcast, Dr. Tom Moorcroft sits down with Dr. Myriah Hinchey, a renowned naturopathic physician and founder of Lyme Botanicals, to dive deep into the science, benefits, and practical applications of herbal treatments for Lyme and co-infections. 📌 In this video: 0:00 - Introduction to botanical medicine and its role in healing 1:30 - Dr. Hinchey’s journey into naturopathy and Lyme treatment 5:14 - Why Lyme Botanicals was created: Addressing gaps in herbal medicine 10:45 - The science behind herbs like Japanese knotweed, cat’s claw, and cryptolepis 15:22 - How to optimize herbal protocols for maximum effectiveness 20:10 - The importance of dosing frequency and consistency 25:35 - Tips for making herbal tinctures palatable (even for kids!) 30:50 - The role of G3 in detoxification and immune support 35:15 - Mindset and lifestyle changes for long-term healing 40:00 - Upcoming Lyme Bytes Symposium and community resources 🔍 Key Topics Covered: Herbal medicine for Lyme disease and co-infections Synergistic effects of botanicals vs. pharmaceuticals How to source high-quality, potent herbs Practical tips for incorporating herbs into daily routines The critical link between gut health, detox, and immune function 💡 Featured Products & Resources: Lyme Botanicals: G3M for detox support: Lyme Bytes Symposium: #LymeDisease #BotanicalMedicine #NaturalHealing #HerbalRemedies #ChronicIllness #ImmuneSupport #Detox Click the link below to visit my Lyme Disease practitioner certification program now! 🍃 Check out more health tips and resources at: 🌐 Website - https://www.originsofhealth.com / https://www.tommoorcroft.com / 📷Instagram: / drtommoorcroft 🎥Facebook: TomMoorcroft, OriginsOfHealth 🧑‍💻LinkedIn: tommoorcroftdo 🐦Twitter: / originsofhealth 🎵Tiktok: / drtommoorcroft /episode/index/show/fullcuplife/id/37778775

Mold, Lyme & True Healing: Dr. Jill Crista on Science, Spirit & Breaking Free 08/12/2025

Marty Ross Reveals The BEST Way to Achieve Your Health Goals in 2025 04/11/2025

Marty Ross Reveals The BEST Way to Achieve Your Health Goals in 2025 🚨 Marty Ross MD Reveals The BEST Way to Achieve Your Health Goals in 2025 🚨 Struggling with chronic illness, Lyme disease, or unexplained health issues? Discover Dr. Marty Ross’s groundbreaking integrative medicine strategies to transform your wellness journey in 2025! In this must-watch podcast episode, renowned holistic health expert Marty Ross MD shares science-backed protocols for Lyme disease treatment, holistic health optimization, and long-term healing. 🔍 In This Podcast, You’ll Learn: ✅ Top Lyme Disease Signs You Can’t Afford to Ignore in 2025 ✅ Integrative Medicine Secrets to Boost Immunity & Reverse Chronic Symptoms ✅ Dr. Ross’s Step-by-Step Holistic Health Plan for Energy, Mental Clarity, & Pain Relief ✅ Cutting-Edge Lyme Disease Treatment Protocols (Backed by Latest Research) ✅ How to Tailor Your Healthcare Approach for Personalized, Sustainable Results 👉 Don’t forget to LIKE and SUBSCRIBE for more expert insights on integrative medicine, holistic health, and beating Lyme disease in 2025! Connect with Dr. Ross - Click the link below to visit my Lyme Disease practitioner certification program now! 🍃 Check out more health tips and resources at: 🎙️ My Podcast - The Lyme Insider 🌐 Websites - / / 📷Instagram: / drtommoorcroft 🎥Facebook: TomMoorcroft, OriginsOfHealth 🧑‍💻 LinkedIn: tommoorcroftdo 🐦Twitter: / originsofhealth 🎵Tiktok: / drtommoorcroft 🎙 Episode Highlights 00:00 – The power of placebo: Can we harness it to heal? 01:04 – Dr. Marty Ross joins to share his journey into integrative Lyme care. 02:29 – From residency to writing health policy to founding TreatLyme.net. 06:46 – First Lyme patient: A misdiagnosis that opened Marty’s eyes. 09:14 – The Ross Protocol: A foundation rooted in chronic fatigue research. 11:50 – What “outcomes-based medicine” really means. 14:05 – Exploring SOT and the placebo question. 17:01 – MyLymeData results: What actually helps people feel better? 20:01 – Hyperbaric oxygen, ozone, and IV vitamin C—what’s legit? 23:01 – Mindset, meditation, and rewriting your internal script. 26:11 – Antibiotics vs. herbs: How to decide and who should decide. 31:04 – Barriers to healing: Financial strain and lack of support. 34:40 – How long COVID helped validate chronic Lyme. 37:02 – FDA changes Lyme test criteria—huge win for the community. 41:56 – Emerging (and overhyped?) therapies: Stem cells, plasmapheresis, LDI. 45:22 – Preventing chronic Lyme through early treatment. 49:04 – Longevity science meets chronic illness: fasting, senolytics, gut rehab. 55:02 – Marty’s new project: Boldality – a site for vibrant aging. 58:36 – Coaching patients through fear and resistance with empathy. 01:00:03 – Health coach mindset: helping patients overcome obstacles. 01:03:57 – Collective progress: Changing the science by working together. 01:07:00 – 85% of chronic Lyme patients can get substantially better—with the right support. /episode/index/show/fullcuplife/id/36099370

Demystifying Lyme Disease Testing with Dr. Joe Burrascano, MD 10/07/2024

Demystifying Lyme Disease Testing with Dr. Joe Burrascano, MD In this episode of The Lyme Insider, we sit down with Dr. Joe Burrascano, MD, a leading expert in Lyme disease testing, to discuss the complexities of diagnosing Lyme disease and its co-infections. This interview dives deep into the challenges faced by patients and healthcare professionals alike, as we explore the latest advancements in testing technologies, how co-infections affect diagnosis, and the impact of the immune system on chronic Lyme disease. Key Discussion Points: Common Misconceptions in Lyme Disease Testing Why Lyme testing is often misunderstood by both patients and healthcare providers, and the importance of education in improving diagnosis accuracy. Limitations of Early Lyme Disease Strains How the original Lyme strain, B31, isolated from a tick, may not represent all cases of Lyme disease across the country, leading to potential diagnostic gaps. The Challenge of Co-Infections The role of co-infections like Babesia and Bartonella in complicating both diagnosis and treatment, and what patients should be aware of when they receive Lyme disease testing. Indirect vs. Direct Testing Methods A breakdown of the differences between indirect tests (which measure immune response) and direct tests (which detect the organism), and how doctors should decide which test is appropriate. How Antibody Levels Change During Treatment A look at how Lyme disease treatment can alter antibody levels over time, and what these changes reveal about a patient’s progress and infection status. The Importance of Recombinant Technology in Testing How advancements like recombinant technology are improving the accuracy of Lyme disease testing, overcoming the shortcomings of traditional methods like the ELISA and Western blot. The Immune System's Role in Chronic Lyme Disease Exploring the immune response in chronic Lyme patients and how newer tests like IGXSpot, which measure T-cell activity, provide a clearer picture of these patients’ conditions. Testing During Symptom Flares Why testing during Lyme disease symptom flares or treatment pauses can often yield more accurate results, and the science behind these recommendations. New Technologies for Early Lyme Detection How cutting-edge tests from iGenex are changing the landscape of early Lyme detection, and why early diagnosis is crucial for better patient outcomes. Personalized Lyme Treatment Based on Testing How to tailor Lyme disease treatment plans according to specific test results, particularly for patients dealing with chronic Lyme or multiple co-infections. Guest Bio: Dr. Burrascano is an expert in Lyme disease research and testing, with years of experience in diagnosing and treating tick-borne illnesses. They have worked closely with iGenex to advance Lyme disease testing technologies and provide better diagnostic tools for healthcare professionals and patients alike. Key Takeaways for Listeners: Understanding why Lyme disease testing can be complex and how to navigate through the different options available. The importance of co-infections in Lyme disease diagnosis and treatment. How new testing methods and technologies are improving the accuracy of Lyme disease diagnosis. Tune in to gain valuable insights into the latest advancements in Lyme disease testing and how to approach diagnosis and treatment more effectively. /episode/index/show/fullcuplife/id/33365857

Unveiling the Hidden Parasite: Dr. Eboni Cornish on Chronic Illness 07/03/2024

Understanding Video Game Addiction with Dr. Koichi Tanji 07/03/2024

The Mind-Blowing Truth About Bartonella Most Doctors Don't Know | With Dr. Ed Breitschwerdt 04/23/2024

The Mind-Blowing Truth About Bartonella Most Doctors Don't Know | With Dr. Ed Breitschwerdt Summary Dr. Ed Breitschwerdt discusses his interest in Bartonella research and the challenges associated with studying this bacteria. He explains the discovery of Bartonella and its unique aspects, including the various vectors and modes of transmission. The prevalence of Bartonella and the challenges in diagnosing the infection are also discussed. Dr. Breitschwerdt highlights the difficulties in testing and diagnosing chronic Bartonella infections and the use of digital PCR for more accurate detection. The chapter concludes with a discussion on the pathophysiology of chronic Bartonella infection. The conversation explores the challenges in accurately diagnosing Bartonella infections and the differences in results from different labs. It highlights the importance of using the correct isolates of the organism for testing and the prevalence of different strains. ThKe discussion also touches on the phenomenon of patients stopping the production of antibodies to Bartonella and the interplay between acute and chronic infections. The conversation emphasizes the need for better diagnostic tests and the development of a vaccine to protect animals and humans from Bartonella infections. Takeaways Bartonella is a complex bacteria with various vectors and modes of transmission. Diagnosing Bartonella infection, especially chronic cases, can be challenging. Digital PCR is a promising tool for more accurate detection of Bartonella. Chronic Bartonella infection can lead to a range of symptoms and recrudescence. Different labs may use different isolates of Bartonella, leading to different results in testing. Patients may stop producing antibodies to Bartonella, making serology testing less reliable. Exposure to Bartonella species is common, and many individuals may be asymptomatic carriers. Bartonella infections may contribute to a spectrum of neurologic and neuropsychiatric diseases. The development of a diagnostic test and a vaccine for Bartonella are important goals for future research. Chapters 00:00 Introduction and Background 00:42 Interest in Bartonella Research 05:38 Challenges and Unique Aspects of Bartonella 08:37 Transmission of Bartonella 11:11 Vectors and Transmission to Humans 14:58 Prevalence of Bartonella and Challenges in Diagnosis 29:35 Chronic Bartonella Infection and Recrudescence 32:20 Pathophysiology of Chronic Bartonella Infection 36:06 Diagnostic Challenges and Digital PCR 41:13 Challenges in Accurate Diagnosis 42:02 Different Results from Different Labs 42:16 Different Isolates of the Organism 43:42 Prevalence of Bartonella Henselae Strains 44:41 Patients Stop Making Antibodies 45:56 Interplay Between Acute and Chronic Infections 46:45 Serofast State in Bartonella Henselae 47:21 Exposure to Bartonella Species 48:19 Testing Blood Donors for Bartonella 49:47 Role of Bartonella in Neurologic Diseases 52:43 Symptoms of Bartonella Infection 54:03 Understanding Bartonella on a Cellular Basis 57:34 Developing a Diagnostic Test for Bartonella 01:00:09 Vaccine Target for Bartonella 01:11:44 Protecting the Human-Animal Bond 01:18:03 Future Goals: Diagnostic Test and Vaccine Dr. Ed Breitschwerdt, DVM , DACVIM about Dr. Breitschwerdt and his work at NC State University about Dr. Breitschwerdt’s work at Galaxy Diagnostics Tom Moorcroft, DO Learn more about Dr. Tom’s . /episode/index/show/fullcuplife/id/30949098

Advancements in Babesia Research and Clinical Implications | With Dr. Choukri Ben Mamoun and Dr. Tim Sellati 03/12/2024

Advancements in Babesia Research and Clinical Implications | With Dr. Choukri Ben Mamoun and Dr. Tim Sellati Summary In this conversation, I’m joined by Dr. Choukri Ben Mamoun and Dr. Tim Sellati to discuss Dr. Ben Mamoun’s recent study on the use of combination therapy for the treatment of Babesia infection entitled: Tafenoquine-Atovaquone Combination Achieves Radical Cure and Confers Sterile Immunity in Experimental Models of Human Babesiosis. We explore the key findings of the study, including the use of immunocompromised mouse models and the potential for long-lasting immunity. The conversation also delves into the importance of understanding the differences between tick-borne infections and the challenges of translating research findings into clinical practice. The discussion highlights the need for further research on dosing and the therapeutic index of different drugs. Overall, the conversation provides valuable insights into the current understanding of Babesia treatment and the potential for future advancements. The conversation covers topics such as combination therapy and resistance, dormant parasites and relapse, terminology and immunocompromised, immune dysregulation and cold exposure, diagnostic testing for Babesia, improving diagnostic testing, and the goal of helping patients. Key Takeaways Combination therapy with tafenoquine and atovaquone has shown promising results in the treatment of Babesia infection. Immunocompromised mouse models are valuable tools for studying the efficacy of different treatments. Understanding the differences between tick-borne infections is crucial for accurate diagnosis and treatment. Further research is needed to determine optimal dosing and the therapeutic index of different drugs for Babesia treatment. Recrudescence and treatment failure are important considerations in Babesia treatment. Combination therapy can reduce the probability of resistance in parasites. Dormant parasites may be responsible for relapse in Babesia infections. The terminology used in scientific research may differ from the general public's understanding. Factors like sleep, stress, and nutrition can contribute to immunocompromised states. Diagnostic testing for Babesia needs improvement to reduce false negatives and false positives. The ultimate goal is to help patients get better by finding the right diagnosis and treatment. There is a need for collaboration between clinicians, researchers, and patients to advance the understanding and treatment of tick-borne infections. Chapters 00:00 Introduction and Overview 03:00 The Study and Key Findings 06:35 Understanding the Research and Clinical Implications 11:56 The Importance of Animal Models 14:43 Immunocompromised Mouse Models 23:22 Differences Between Tick-Borne Infections 26:34 Combination Therapy: Tafenoquine and Atovaquone 32:26 Dosing and Therapeutic Index 36:48 Artemisinin as a Treatment Option 46:20 Recrudescence and Treatment Failure 48:23 Combination Therapy and Resistance 50:24 Dormant Parasites and Relapse 53:18 Terminology and Immunocompromised 56:15 Immune Dysregulation and Cold Exposure 59:14 Diagnostic Testing for Babesia 01:03:22 Improving Diagnostic Testing 01:12:12 The Goal of Helping Patients 01:20:22 Caring and Finding the Truth Link to the paper we discussed: Tafenoquine-Atovaquone Combination Achieves Radical Cure and Confers Sterile Immunity in Experimental Models of Human Babesiosis - Learn More About My Guests: Choukri Ben Mamoun, PhD - Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis; Affiliated Faculty, Yale Institute for Global Health Timothy Sellati, PhD - Chief Scientific Officer, Global Lyme Alliance Learn more about Dr. Tom’s . /episode/index/show/fullcuplife/id/30338358