#399: Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam
LONGEVITY with Nathalie Niddam
Release Date: 12/26/2025
LONGEVITY with Nathalie Niddam
Today, I’m joined by a lineup of trailblazers in the science of longevity: , , , , , and . Together we dig into some of the most persistent myths and cutting-edge research shaping how we age—including why “eat less, move more” misses the mark, what really causes skin cancers, breast cancer screening risks, and the often-overlooked ripple effects of perimenopause. Links to full episodes: Episode Timestamps: Welcome & podcast overview ... 00:00:00 Longevity habits handout & sponsor plug ... 00:00:48 Clean protein choices & contamination risks ......
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by , from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father’s pharmacy, to experimenting with early nootropic formulas, and ultimately becoming a sought-after educator in the world of biohacking. Episode Timestamps: Podcast introduction and guest welcome ... 00:00:00 Lucas Aoun’s journey into biohacking ... 00:04:13 Innovative supplement formulation and teacrine ... 00:10:00 Dopamine’s role in motivation and productivity ... 00:32:09 Bioindividual...
info_outlineLONGEVITY with Nathalie Niddam
Today, it’s just me, and we’re doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives and high-tech hacks to focus on something fundamental—free, practical strategies to help you manage stress. Chronic stress is sneaky in how it accelerates aging, impacts your telomeres, and undoes even the most powerful interventions, but thankfully, there are simple ways we can start to turn things around. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Immune...
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by —founder of Biocybernaut and a true pioneer in the world of neurofeedback. With over four decades spent mapping how our brainwaves shape emotions, performance, and even identity, Dr. Hardt has helped reframe the conversation around unlocking human potential, making cutting-edge brain training accessible to seekers, creatives, and everyday biohackers alike. Download a FREE copy of his book “The Art of Smart Thinking” at Episode Timestamps: Intro to Longevity Podcast and host ... 00:00:00 Introduction to Dr. James Hardt and neurofeedback ... 00:00:34 Alpha...
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m sitting down with the irrepressible , renowned biotech innovator and founder of , a groundbreaking formula for liver health. Siggi’s story is deeply personal—motivated by the loss of loved ones to liver disease, he’s made it his life’s mission to demystify liver health and help others avoid the fate that touched his own family. Visit code: NAT for 5% off Episode Timestamps: Introduction and podcast themes ... 00:00:00 Eastern vs. Western liver views ... 00:07:09 Why liver health is central to longevity ... 00:09:28 Hidden toxins: everyday exposures ......
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly with Professor Vladimir Khavinson—the scientist who discovered and developed bioregulator peptides—and has spent the last eight years leading some of the most exciting field research in this space. Episode Timestamps: Welcome and introduction to Longevity Podcast ... 00:00:00 Origins and early use of bioregulator peptides in Soviet research ... 00:05:39 Organ-specific peptide...
info_outlineLONGEVITY with Nathalie Niddam
Today, I'm joined by the incomparable —a true pioneer in shifting healthcare from “what’s wrong with you” to “what’s right with you.” Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can’t ignore, and how something as simple as a toxicity panel can completely change your health trajectory. Episode Timestamps: Welcome and episode introduction ......
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by the innovative , whose name couldn’t be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mind. After growing up with severe OCD and witnessing the rising tide of global anxiety, he became obsessed with one question: Why are we all stuck in fight or flight, and what can we actually do about it? Use code NAT at for 15% off Episode Timestamps: Introduction to Longevity Podcast and Host ... 00:00:00 The Rise of Anxiety and Mental Health Innovation ... 00:05:19 Why Modern Society...
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by the incredible , a true pioneer in natural beauty and holistic health. Nadine is well known for bridging the gap between ancient wisdom and modern science, and in this episode, she completely redefines how we look at hair care—not just as a cosmetic routine, but as a form of biological reset. She shares how everything from stress to toxins and even your shower water can disrupt the delicate ecosystem of your scalp, and how her simple, nature-inspired rituals can help restore balance. Past episode: Study with Rosemary: Episode Timestamps:...
info_outlineLONGEVITY with Nathalie Niddam
Today, I’m joined by Dr. Brad Currier, Manager of Clinical Trials at and an expert in the world of muscle and aging research. Brad is on the cutting edge of mitochondrial science, and in this episode, he helps us unravel the mysteries of why some 80-year-olds are still crushing it in the gym while others struggle to get up the stairs. We dive into his fascinating research on mitophagy—our bodies’ system for recycling dysfunctional mitochondria—and what it means for muscle health, strength, and vibrant aging. Visit and use code nat20 for 20% off your purchase. Episode...
info_outlineToday, I’m joined by a lineup of trailblazers in the science of longevity: Ben Azadi, Dr. Teo Soleymani, Dr. Carrie Jones, Ian White, Dr. Robert Lufkin, and Dr. Jenn Simmons . Together we dig into some of the most persistent myths and cutting-edge research shaping how we age—including why “eat less, move more” misses the mark, what really causes skin cancers, breast cancer screening risks, and the often-overlooked ripple effects of perimenopause.
Links to full episodes:
- #333: Keto Myths, Carb Days, and Why Calories Don’t Count | Ben Azadi on Breaking the Weight Loss Cycle
- Episode 338: How the Sun ACTUALLY Impacts Skin Aging and Cancer Risk: Skin Cancer Controversies, Sun Safety Secrets, and Anti-Aging Breakthroughs With Teo Soleymani, MD
- Episode 376: Survival Tips for Perimenopause, NEW At-Home Hormone Testing & Bioidentical Myths With Dr. Carrie Jones
- Episode 350: Nature’s Longevity CODE Revealed: Exosomes, Plasma HACKS & the Real Science of Aging | With Dr. Ian White
- Episode 318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin
- Episode 300: Breast Cancer Overdiagnosis, Mammogram Myths, The REAL Risks For Women And Bold NEW Alternatives With Dr. Jenn Simmons
Episode Timestamps:
Welcome & podcast overview ... 00:00:00
Longevity habits handout & sponsor plug ... 00:00:48
Clean protein choices & contamination risks ... 00:01:25
Calorie focus vs. hormones in weight loss ... 00:02:42
Why calories in/calories out fails ... 00:03:27
Cellular inflammation & gut microbiome in weight ... 00:04:43
Healthy, flexible metabolism over fast metabolism ... 00:07:51
Sun exposure, genetics & skin cancer ... 00:08:02
Sunscreen myths & ingredient safety ... 00:11:47
Perimenopause symptoms beyond hot flashes ... 00:12:27
Hormone replenishment: lifestyle + medical strategies ... 00:15:35
Breaking menopause myths & self-education ... 00:19:05
Blood factors & parabiosis in aging ... 00:21:37
Plasma exchange — practical and scientific updates ... 00:26:01
Western medicine vs. chronic disease reality ... 00:28:07
Breast cancer screening & over-treatment concerns ... 00:33:16
Hormone therapy after menopause—timing & benefits ... 00:37:07
Our Amazing Sponsors:
PW1 protein powder is third-party tested for more than 200 contaminants, and Puori was the only brand that earned the Clean Label Project Transparency Certificate. That level of disclosure is rare. And refreshing. If you want protein that supports your goals — without the guesswork — go to Puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site.
Manukora - Now in NEW Glass Jars - This isn’t regular honey. Manukora’s bees collect nectar from the Manuka tea tree, which packs 3x more antioxidants and prebiotics than normal honey. Plus it naturally contains MGO, that rare antibacterial compound. Head to MANUKORA.com/NAT to save up to 31% plus get $25 worth of free gifts with the Starter Kit.
Nat's Links: