#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff
LONGEVITY with Nathalie Niddam
Release Date: 01/06/2026
#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff
LONGEVITY with Nathalie Niddam
Today, I’m joined by the insightful , renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal “aha” moments that led her to champion true weight health, not just weight loss. Episode Timestamps: Welcome and introduction to the Longevity Podcast ... 00:00:00 Personal experiences shaping nutrition philosophy ... 00:05:59 Influence of...
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#400: Why Chasing Muscle for Longevity Might Backfire: The Real Keys to Aging Well With Joel Greene.
LONGEVITY with Nathalie Niddam
Today, I’m excited to bring back the always thought-provoking , author of “The Immunity Code” and “The Way,” for a fresh conversation on why true longevity is about so much more than how much muscle you have or the latest diet trend you’re following. Joel Greene opens up about the hard lessons he’s learned from decades of self-experimentation and reveals why chasing that ideal gym physique might actually backfire as you age. Episode Timestamps: Welcome & episode introduction ... 00:00:00 The evolving nature of health and homeostasis ... 00:08:29 Beware rigid diet...
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#399: Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam
LONGEVITY with Nathalie Niddam
Today, I’m joined by a lineup of trailblazers in the science of longevity: , , , , , and . Together we dig into some of the most persistent myths and cutting-edge research shaping how we age—including why “eat less, move more” misses the mark, what really causes skin cancers, breast cancer screening risks, and the often-overlooked ripple effects of perimenopause. Links to full episodes: Episode Timestamps: Welcome & podcast overview ... 00:00:00 Longevity habits handout & sponsor plug ... 00:00:48 Clean protein choices & contamination risks ......
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#398: The Dopamine Biohack | Brain Chemistry, Motivation & Testosterone Secrets Revealed With Lucas Aoun
LONGEVITY with Nathalie Niddam
Today, I’m joined by , from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father’s pharmacy, to experimenting with early nootropic formulas, and ultimately becoming a sought-after educator in the world of biohacking. Episode Timestamps: Podcast introduction and guest welcome ... 00:00:00 Lucas Aoun’s journey into biohacking ... 00:04:13 Innovative supplement formulation and teacrine ... 00:10:00 Dopamine’s role in motivation and productivity ... 00:32:09 Bioindividual...
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#397: STRESS: The Silent Accelerator of Aging (10 Free Hacks Rewiring Your Longevity) | Calm Amid Chaos With Nat Niddam
LONGEVITY with Nathalie Niddam
Today, it’s just me, and we’re doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives and high-tech hacks to focus on something fundamental—free, practical strategies to help you manage stress. Chronic stress is sneaky in how it accelerates aging, impacts your telomeres, and undoes even the most powerful interventions, but thankfully, there are simple ways we can start to turn things around. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Immune...
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#396: From Trauma to Transcendence: Alpha Training, Elite Creativity Gains, and Reversing Aging — With Dr. James Hardt
LONGEVITY with Nathalie Niddam
Today, I’m joined by —founder of Biocybernaut and a true pioneer in the world of neurofeedback. With over four decades spent mapping how our brainwaves shape emotions, performance, and even identity, Dr. Hardt has helped reframe the conversation around unlocking human potential, making cutting-edge brain training accessible to seekers, creatives, and everyday biohackers alike. Download a FREE copy of his book “The Art of Smart Thinking” at Episode Timestamps: Intro to Longevity Podcast and host ... 00:00:00 Introduction to Dr. James Hardt and neurofeedback ... 00:00:34 Alpha...
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#395: Brain Fog, Anger, Detox Secrets & The Truth About Diet Sodas | Unlocking LIVER Longevity With Siggi Clavien
LONGEVITY with Nathalie Niddam
Today, I’m sitting down with the irrepressible , renowned biotech innovator and founder of , a groundbreaking formula for liver health. Siggi’s story is deeply personal—motivated by the loss of loved ones to liver disease, he’s made it his life’s mission to demystify liver health and help others avoid the fate that touched his own family. Visit code: NAT for 5% off Episode Timestamps: Introduction and podcast themes ... 00:00:00 Eastern vs. Western liver views ... 00:07:09 Why liver health is central to longevity ... 00:09:28 Hidden toxins: everyday exposures ......
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#394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence
LONGEVITY with Nathalie Niddam
Today, I’m joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly with Professor Vladimir Khavinson—the scientist who discovered and developed bioregulator peptides—and has spent the last eight years leading some of the most exciting field research in this space. Episode Timestamps: Welcome and introduction to Longevity Podcast ... 00:00:00 Origins and early use of bioregulator peptides in Soviet research ... 00:05:39 Organ-specific peptide...
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#393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso
LONGEVITY with Nathalie Niddam
Today, I'm joined by the incomparable —a true pioneer in shifting healthcare from “what’s wrong with you” to “what’s right with you.” Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can’t ignore, and how something as simple as a toxicity panel can completely change your health trajectory. Episode Timestamps: Welcome and episode introduction ......
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#392: Biohacking the MIND: 78% Anxiety Remission, Vagus Nerve Secrets & The Mental Health Revolution | Zenbud’s Jon Hacker Unlocks REST
LONGEVITY with Nathalie Niddam
Today, I’m joined by the innovative , whose name couldn’t be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mind. After growing up with severe OCD and witnessing the rising tide of global anxiety, he became obsessed with one question: Why are we all stuck in fight or flight, and what can we actually do about it? Use code NAT at for 15% off Episode Timestamps: Introduction to Longevity Podcast and Host ... 00:00:00 The Rise of Anxiety and Mental Health Innovation ... 00:05:19 Why Modern Society...
info_outlineToday, I’m joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal “aha” moments that led her to champion true weight health, not just weight loss.
Episode Timestamps:
Welcome and introduction to the Longevity Podcast ... 00:00:00
Personal experiences shaping nutrition philosophy ... 00:05:59
Influence of marketing on nutrition decisions ... 00:09:01
Big revelations: digestion, GLP-1, and health ... 00:16:43
The power of personalization in nutrition ... 00:19:59
The “Mr. Pizza Pop” case and behavioral change ... 00:23:03
Digestion as the foundation before diet quality ... 00:27:05
Dangers of generic “healthy diet” advice ... 00:36:01
GLP-1 medications: promise, risks, and prerequisites ... 00:40:10
Who truly needs GLP-1 versus lifestyle change alone ... 00:43:09
Muscle, bone, and shifting focus to building health ... 00:51:30
Nutrient intake, fiber, and supplement personalization ... 00:55:11
Digestive enzymes and optimizing digestion ... 01:03:10
Food noise, satiety, and psychological freedom ... 01:07:29
Ongoing assessment: tracking weight, fat, muscle ... 01:15:19
Weaning off GLP-1 and the importance of professional support ... 01:18:32
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