Libsyn Directory

Ep. 13: Chef Andrew Gruel: Learning to Cook Again—with Dr. Brian Kerley

Release Date: 02/01/2024

Ep. 26: How To Lie With Science (Nick Jikomes Livestream)

Tucker Goodrich: Debugging Life

Introduction Nick asked me to do a YouTube livestream to go over some research he had been doing. He drilled down on a reference in a high-profile cardiology guideline article and discovered that the authors had inverted the research finding in the referenced paper to claim the inverse of what it actually showed. We discussed this, and then I gave some more context about the matter and one of the authors. Guest info “Nick Jikomes is a neuroscientist, plant chemistry researcher, data scientist, and podcast host. He received a PhD in Neuroscience from Harvard University and a Bachelor of...

Ep. 25: Is Mikhail Shchepinov "Breaking The Chains of Aging"?

Tucker Goodrich: Debugging Life

Introduction It's well-known that lipid peroxidation is involved in aging and longevity. But what can we do about it? Dr. Shchepinov has been researching using deuterium to 'shore up' the PUFAs like those in seed oils to prevent them become toxic metabolites. He's had some interesting successes, and we discuss at length his new book: “Breaking the Chains of Aging”. Amazon link: Book website Research: Biography: Mikhail Shchepinov trained in Moscow (PhD, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, 1994), then moved to Oxford to work on DNA microarray technology,...

Ep. 24: Does Deuterium Cause Chronic Disease? With Prof. John Speakman

Tucker Goodrich: Debugging Life

Introduction I am honored to be joined by John Speakman, a leading authority on energy balance in animals, and in the use of the doubly-labeled water method of determining energy balance. This has led him into the study of obesity, among other topics, where he has become a recognized expert. Our discussion was prompted by his recent paper, “Total Daily Energy Expenditure Has Declined Over the Past Three Decades Due to Declining Basal Expenditure, Not Reduced Activity Expenditure”, which casts a new light onto the world pandemic of obesity. In addition to discussing a few of the papers that...

Ep. 23: "Ep 23 Doctors Should Tell Patients that High Linoleic Acid Seed Oils are Unhealthy"—with Raphael Sirtoli and Dave Feldman

Tucker Goodrich: Debugging Life

Introduction So apparently there is some demand for discussion/debate on the topic of seed oils and health. Dave Feldman (Ep. 9) had considered doing this at his recent conference, but couldn’t fit in the time. He’s since regained interest in the idea, and reached out to Andreas Eenfeldt and Ted Naiman, who have expressed skepticism. They replied: “We decline as we feel this debate is a distraction. The reason is that we see no good scientific evidence for replacing any source of added pure fat with another. It's not the right question.” Since there’s so much interest, and clearly...

Ep. 22: John Speakman—What Causes Obesity?

Tucker Goodrich: Debugging Life

Ep. 21: How Seed Oils Promote Cancer—with Matt Quinn and Dr. Brian Kerley

Tucker Goodrich: Debugging Life

Introduction Cancer is the second-leading killer of Americans, and is increasing both around the world and increasingly affecting younger and younger people. It’s obviously important to understand what environmental factors might affect our susceptibility to the various cancers. Here we discuss what I think is a key paper showing a link between our environment, genetic mutation, and metabolic dysfunction in cancer cells. “The Major Lipid Peroxidation Product, Trans- 4-Hydroxy-2-Nonenal, Preferentially Forms DNA Adducts at Codon 249 of Human P53 Gene, a Unique Mutational Hotspot in...

Ep. 20: Are Seed Oils a Problem?—with Jacob Hands (Ep. 19 Excerpt)

Tucker Goodrich: Debugging Life

Ep. 19: Jacob M. Hands—What's Wrong With Fish Oil (Chocolate too!?!)?

Tucker Goodrich: Debugging Life

Introduction What about fish oil? Is it a problem due to oxidation and contamination? Is it beneficial to health as many claim or is it a PUFA that’s bad for your health? Jacob recently published an analysis of various fish oils with the team at Consumer Labs, looking at oxidative toxicity and purity of a wide variety of commercially available fish oils. We discuss omega-3 and health, fish oils and oxidation, the science of seed oils and health, and, as a bonus, the problem with chocolates. This is definitely a bit of a geek fest, so let me know if you have any questions. Guest info Jacob...

Ep. 18: What Causes Insulin Resistance?—with Matt Quinn and Dr. Brian Kerley

Tucker Goodrich: Debugging Life

Diabetes, broadly defined, afflicts greater than 50% of the U.S. population. The hallmark of type 2 diabetes is insulin resistance. While many are unable to answer the question of why a formerly rare disease now afflicts the majority of the population, we go over research dating back to 1964 that makes it clear that we have a pretty good idea of what causes insulin resistance. Scientists can easily induce insulin resistance in humans. How do they do it, and what might it tell us about what has caused our epidemic of diabetes? Guest info Matt Quinn Biography: TL;DR Here's what I...

Ep. 17: Making Better Meat—Autumn Smith and John Etchart

Tucker Goodrich: Debugging Life

Introduction We’re honored to be joined today by Autumn Smith of Paleovalley and John Etchart of Wild Pastures. These related companies (John is Autumn’s brother-in-law) work to deliver healthy, regeneratively-farmed foods to their customers. “At Paleovalley, our mission is to help people reclaim vibrant health. We provide products that prioritize nutrient density in an industry that prioritizes everything else. We believe that every dietary choice and every added ingredient is a powerful opportunity to love and care for oneself.” Wild Pastures: “Turning The Page To A Healthier You...

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Introduction

Brian and I are honored to be joined by the illustrious Chef Andrew Gruel. He tells us the story of how he got into cooking, how he had to learn to cook again after discovering that his academic chef training left out natural fats, and the impact using proper fats has had on his health, the health of his staff, and his customers in his latest restaurant venture.

We also have an extensive and very interesting discussion on fish, fish farming, and the health benefits of eating fish.

Guest info

Web: www.chefgruel.com (It throws a security error…)

X: https://twitter.com/ChefGruel

Substack: “The Food Porn Master”! https://substack.com/@andrewgruel

Instagram: https://www.instagram.com/andrewgruel/

Calico Fish House: https://calico-restaurant.com/

Biography:

“Andrew Gruel, a graduate of Johnson & Wales University, is a food entrepreneur and television personality – he is the Founder of Slapfish Restaurant Group (27 locations), the award-winning food truck turned international brick and mortar, based out of Huntington Beach, CA and currently CEO and founder of American Gravy Restaurant Group which comprises Calico Fishhouse, Big Parm Pizza, Two Birds Chicken, Butterleaf, Lolo’s Tacos and 101 Burger.

“Andrew has appeared on multiple television series including his most recent role as a judge on Food Network’s “Chopped Junior” with Megan Markle. He was the Host of FYI Series “Say It To My Face”, as well as a judge on Food Network’s “Food Truck Face Off.” He has made appearances on the TODAY show, Fox News, CNN, NBC Nightly News, PBS, Cooking Channel, and has been featured in numerous publications including The Wall Street Journal, Forbes, Men’s Health, Food & Wine magazine, USA Today, Entrepreneur and Nation’s Restaurant News. He was named Top 25 Business Executives for Fast Casual magazine as well as featured in Nation’s Restaurant News’ 2017 Power List. In 2013 he was named top 40 under 40 entrepreneurs in Orange County. He and his wife Lauren Gruel were named Pandemic Heroes by Restaurant Business Magazine alongside Guy Fieri and Jose Andres. He is currently the Co-Host of The SoCal Restaurant Show on AM 830 and a regular contributor on various national news channels.”

http://www.chefgruel.com/index.php/about-us.html

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