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Collagen: What Does It Do & Are Supplements Worth The Money?

Quest For Longevity

Release Date: 11/26/2025

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More Episodes

Do collagen supplements live up to the hype? This evidence-based episode cuts through the marketing claims to reveal what science really says about collagen supplements. We explore what collagen is, how it works in your body, and examine the latest clinical trials and meta-analyses on skin health, joint pain, bone density, and muscle function.

Perfect for anyone considering collagen or wanting to understand the science behind this billion-dollar industry.

 

Quality Health Supplements

I use WeightWorld supplements. They produce great value, quality products and I’ve been very pleased with the results.

(I am affiliated with WeightWorld and receive a small commission if you buy via my link or use my checkout code. This doesn’t cost you any extra and anything I earn helps me to devote more time to researching and producing this podcast.)

 

Research Sources

Collagen: What It Is, Types, Function & Benefits

Biochemistry, Collagen Synthesis - StatPearls

The Collagen Family

Collagens—structure, function, and biosynthesis

Collagen

Collagen

Type I Collagen - an overview

A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold

Regulation of Collagen I and Collagen III in Tissue Injury and Regeneration

Absorption and metabolism of orally administered collagen hydrolysates evaluated by the vascularly perfused rat intestine and liver in situ

Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals

Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals

Collagen Powder Absorption And Bioavailability

Does Collagen Powder Survive Digestion? Absorption Explained

How Collagen Works Inside Your Body: The Science Behind Absorption

Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

A Clinical Trial Shows Improvement in Skin Collagen, Hydration, Elasticity, Wrinkles, Scalp, and Hair Condition following 12‐Week Oral Intake of a Supplement Containing Hydrolysed Collagen

Clinical studies and meta-analysis on the effects of collagen, vitamin, and nutrient supplementation for the rejuvenation of collagenic fibers: a systematic review

Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials

Effect of collagen supplementation on knee osteoarthritis: an updated systematic review and meta-analysis of randomised controlled trials

Are Collagen Supplements Helpful for Arthritis?

Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge

Can collagen supplements help improve skin and soothe joint pain?

The Effects of Type I Collagen Hydrolysate Supplementation on Bones, Muscles, and Joints: A Systematic Review

The Effects of Type I Collagen Hydrolysate Supplementation on Bones, Muscles, and Joints: A Systematic Review

Efficacy of collagen peptide supplementation on bone and muscle health: a meta-analysis

Efficacy of collagen peptide supplementation on bone and muscle health: a meta-analysis

Specific Collagen Peptides Improve Bone Mineral Density and Bone Markers in Postmenopausal Women—A Randomized Controlled Study

Expert consensus on specific collagen peptides in osteoporosis management

Collagen Peptide Supplementation and Musculoskeletal Performance: A Systematic Review and Meta-Analysis

Collagen Science Update – March 2024 Edition

Undenatured Type II Collagen (UC-II) in Joint Health and Disease: A Review on the Current Knowledge of Companion Animals

UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study

UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study

Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers

Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers

Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers

Collagen Type II (native): Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews

UC-II Undenatured Type II Collagen for Knee Joint Flexibility: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study

Collagen Types: The Important Differences Between I, II & III

Differences and benefits between hydrolyzed collagen and collagen

Dr. Brad Stanfield: Collagen has No benefits for skin aging?