Dr. Dominic D’Agostino, Ph.D.: The Effects of Ketosis and Fasting on Mitochondrial Health and Epigenetics
Release Date: 01/25/2023
Smarter Not Harder
In this episode of the Smarter Not Harder Podcast, Jodi Duval leads a powerful conversation with Dr. Ted Achacoso, Dr. Scott Sherr, and Dr. Allen Bookatz about burnout in clinical practice—and how to actually prevent it. From saying no to draining patients to finding joy in curiosity and community, the team shares practical tools for sustaining a long, fulfilling career in medicine. Join us as we delve into: Why it’s okay (and sometimes necessary) to fire patients Daily rituals and mindset shifts that protect your energy How practitioner community can prevent isolation and overwhelm...
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What if healing didn’t start with supplements, but with a shift in thought? In this episode of the Smarter Not Harder Podcast, Dr. Scott Sherr sits down with renegade nurse and educator Karen DiMarco to explore how psychosocial stress, identity, and hypervigilance can create—or dissolve—chronic illness. Karen shares her personal health journey, the groundbreaking chronic fatigue study she co-led, and why our thoughts may be the most overlooked variable in healing. Join us as we delve into: The story behind Karen’s recovery from chronic fatigue syndrome Her radical 8-week study that...
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In this episode of the Smarter Not Harder Podcast, the Troscriptions and HOMeHOPe faculty get personal. Dr. Scott Sherr, Dr. Ted Achacoso, and Jodi Duval go behind the curtain on what they’re actually taking, testing, and tossing when it comes to supplements. From methylene blue pessaries to kratom gummies, designer peptides to custom troches—this roundtable reveals how experienced clinicians approach their own protocols, and the often messy process of self-experimentation. Join us as we delve into: The real story behind what's in their supplement drawers How the team thinks about...
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In this episode of the Smarter Not Harder Podcast, Dr. Abid Husain joins Dr. Scott Sherr for a masterclass on cardiovascular health — from cholesterol myths to mitochondrial truth. They explore what truly drives inflammation, plaque formation, and cardiovascular risk, while dismantling the outdated “cholesterol = heart disease” narrative. Whether you're a clinician or simply someone trying to make smarter choices for your heart, this episode offers insight into testing, interventions, and personalized strategies that go beyond basic lipid panels. Join us as we delve into: + Why LDL alone...
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In this episode of the Smarter Not Harder Podcast, we dive into the outrageous, unexpected, and sometimes uncomfortable experiments our hosts have tried in the name of health optimization. From gallbladder flushes and vitamin D megadosing to powerlifting with a colonic and hiking mountains while microdosing, this episode is full of real (and ridiculous) stories. Boomer Anderson, Dr. Scott Sherr, Dr. Ted Achacoso, Jodi Duval, and Dr. Allen Bookatz share the protocols they’ve tested so you don’t have to — and what they actually learned from pushing the limits. Join us as we delve into: ...
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In this episode of the Smarter Not Harder Podcast, Dr. Scott Sherr takes us on a solo deep dive into the myths, history, physiology, and media controversies surrounding methylene blue. From Blue Brains headlines to Huberman posts and clinical dosing strategies, Scott sets the record straight and unpacks why this molecule has become a lightning rod in health optimization conversations. Whether you're new to methylene blue or need clarity on the latest internet debates, this episode gives you science-backed context and a refreshingly clinical perspective. Join us as we delve into: The history...
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In this episode of the Smarter Not Harder Podcast, Bob Troia explores what it means to truly understand yourself through data. With decades of experience in both tech and personal science, Bob shares his journey from building early web innovations to becoming a leader in the quantified self and biohacking space. As the co-founder of Awesome Labs and SuppTrack, Bob discusses how his personal experiments with sleep, glucose, HRV, and nootropics like methylene blue have inspired tools that help others optimize their lives. From spreadsheets to app development, Bob shows how self-tracking can be...
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In this episode of the Smarter Not Harder Podcast, Dr. Larry Palevsky shares his journey from pediatric emergency medicine to a root cause–based approach to healing. Drawing on decades of clinical experience, he explores why suppressing symptoms may interfere with true recovery, and how restoring parasympathetic balance, optimizing nutrition, and reducing environmental inputs can transform both acute and chronic illness—especially in children. Whether you're a practitioner, a parent, or simply someone questioning the conventional medical model, this conversation invites a deeper...
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In this episode of the Smarter Not Harder Podcast, Boomer Anderson, Dr. Scott Sherr, and Dr. Ted Achacoso dive deep into the topic of hydration, debunking common myths and offering practical tips. They clarify the effects of caffeine and alcohol as diuretics and discuss the misconception about clear urine indicating proper hydration. They explore the evolutionary aspects of water's role in biology and provide specific recommendations for daily water intake, emphasizing the importance of a little salt and possibly sugar for optimal hydration. The conversation also covers various methods for...
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