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Fix Chronic Disease at Its Root with Metabolomics & Health Optimization | SNH Podcast #127

Health Optimization Medicine Podcast

Release Date: 06/11/2025

Why You Can’t Out-Supplement a Dysregulated Nervous System | HOMe Podcast #018 show art Why You Can’t Out-Supplement a Dysregulated Nervous System | HOMe Podcast #018

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, Dr. Allen Bookatz, Dr. Ted Achacoso, and Jodi Duval tackle the widespread trend of supplement fatigue. As biohacking becomes a mindset of treating symptoms with heavy stimulants and endless pills, the faculty breaks down why forcing adaptation on an exhausted system only drives the body deeper into a chronic state of inflammatory defense. From the biophysics of the Cell Danger Response (CDR1) to practical parasympathetic upregulation, this roundtable shifts the focus from treating disease to establishing true autonomic safety. Join...

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Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox | HOMe Podcast #017 show art Cellular Safety and the Dangers of Mechanical Blood Microplastic Detox | HOMe Podcast #017

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, our faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, Dr. Allen Bookatz, and Jodi Duval, tackle the recent trend of therapeutic plasma exchange and "blood washing". Moving past the mainstream marketing of plasmapheresis as a longevity cure-all, the team breaks down why mechanical filtering is only a surface-level fix for microplastic toxicity. From the autonomic anxiety caused by biological lockdown to the clinical application of precision metabolomics, this roundtable shifts the conversation from invasive procedures to...

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The HRV Paradox: Why Tracking Your Sleep Makes It Worse | HOMe Podcast #016 show art The HRV Paradox: Why Tracking Your Sleep Makes It Worse | HOMe Podcast #016

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Boomer Anderson, and Jodi Duval) tackles one of the most paradoxical trends in modern biohacking: sleep tracking. Moving past the mainstream obsession with daily device scores, the team breaks down the biochemical realities of how tracking your HRV might actually be sabotaging your sleep architecture. From the autonomic anxiety caused by digital wearables to the clinical application of precision chronobiology, this roundtable shifts the conversation from algorithmic scores to...

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Decoding the Holobiont: The Ecosystem of Ecosystems | HOMe Podcast Special Episode show art Decoding the Holobiont: The Ecosystem of Ecosystems | HOMe Podcast Special Episode

Health Optimization Medicine Podcast

In this special in-person roundtable recorded in Washington, D.C., the HOMeHOPe faculty sit down to decode one of the most important perspective shifts in modern health: the Holobiont. Moving away from the traditional, siloed medical model of "organology" (treating the heart, gut, and brain as isolated systems managed by different specialists), the faculty discusses why true health optimization requires viewing the human body as a complex, interconnected ecosystem of ecosystems. Join us as we delve into: The Holobiont Paradigm: Why you are not just a single organism, but a super-ecosystem...

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Bypass the Fiber Trend & Optimize Your Gut Health | HOMe Podcast #015 show art Bypass the Fiber Trend & Optimize Your Gut Health | HOMe Podcast #015

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, the core faculty (Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz) tackles one of the most misunderstood topics in modern nutrition: fiber. Moving past the mainstream trend of "fiber-maxing," the team breaks down the actual biochemical realities of how different forms of fiber interact with your unique gut microbiome. From the surprising hormonal impacts of over-consuming fiber to the rise of localized conditions, this roundtable shifts the conversation from generic dietary rules to precise, measurable,...

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Why Aging May Be the Root Cause of Chronic Disease | HOMe Podcast #014 show art Why Aging May Be the Root Cause of Chronic Disease | HOMe Podcast #014

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe faculty, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz reunite in person in Washington, D.C.. Moving away from traditional classifications of illness, the team breaks down a powerful paradigm shift: chronic disease and aging are not separate processes—chronic disease is aging. Drawing from the pioneering frameworks of biogerontologist Aubrey de Grey and the SENS Research Foundation, they discuss how flawed metabolism inherently accumulates structural damage long before a clinical diagnosis...

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Health Optimization for Parenting, Pregnancy & Family Life | HOMe Podcast #013 show art Health Optimization for Parenting, Pregnancy & Family Life | HOMe Podcast #013

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, hosts Dr. Scott Sherr and Jodi Duval come together for an intimate, parent-to-parent roundtable. As the only current parents on the HOMeHOPe faculty, they dive deep into the specific biology of preconception, pregnancy, and pediatric health optimization. Moving beyond typical disease management, they explore how to foster both psychological and cellular safety across the entire family unit. Join us as we delve into: The Masterclass Blueprint: Navigating the fastest period of human growth and biological wiring from preconception to...

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What Nobody Told You About Your Gut | HOMe Podcast #012 show art What Nobody Told You About Your Gut | HOMe Podcast #012

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty (Dr. Scott Sherr, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers) dive deep into the unseen world inside your stomach. Moving beyond simple probiotics, they discuss the gut as a "post-natal organ" and explore how the trillions of microbes inside you actually dictate your cravings, your mood, and your immune system. 𝗝𝗼𝗶𝗻 𝘂𝘀 𝗮𝘀 𝘄𝗲 𝗱𝗲𝗹𝘃𝗲 𝗶𝗻𝘁𝗼: •The "tripartite axis" (Gut-Brain-Enteric Microbiota) and how it links directly to treatment-resistant...

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The Problem with Over-Optimization in Modern Health | HOMe Podcast #011 show art The Problem with Over-Optimization in Modern Health | HOMe Podcast #011

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Allen Bookatz, and Dr. Jup Kuipers come together live in studio in Washington, D.C. to discuss the dangers of over-optimization and the "more is better" mentality. They explore real clinical case studies of patients who inadvertently damaged their health by blindly following supplement trends. Join us as we delve into: The dangers of over-supplementing with high-dose Fish Oil and Vitamin B6. How shifting to an "Omega-3 dominant" ratio can actually hinder your immune system's ability to heal injuries. Why...

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Creatine, Cellular Energy, and the Modern Stress Epidemic | HOMe Podcast #010 show art Creatine, Cellular Energy, and the Modern Stress Epidemic | HOMe Podcast #010

Health Optimization Medicine Podcast

In this episode of the Health Optimization Medicine Podcast, the HOMeHOPe Faculty comes together for a roundtable conversation exploring the science and clinical application of creatine. Moving beyond its reputation as just a performance supplement for "gym bros," Boomer Anderson, Dr. Scott Sherr, Dr. Allen Bookatz, and Dr. Ted Achacoso break down how creatine functions as a critical cellular battery buffer. Join us as we delve into: How creatine bypasses the "methylation tax" by saving the body from depleting SAMe reserves to produce energy. Why muscle is a metabolic determinant of...

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More Episodes

In this episode & live round-table of the Smarter Not Harder Podcast, Boomer Anderson sits down with Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Jup Kuipers, and Dr. Allen Bookatz to unpack the shift from “sick-care” to genuine health-care. Drawing on stories from primary care, the ER, and longevity practice, they explain how the Health Optimization Medicine (HOMe) model uses metabolomics, gut testing, and evolutionary biology to keep you thriving—long before disease strikes.

Join us as we delve into:

  • Why traditional, disease-centered medicine struggles with chronic conditions
  • The HOMeHOPe framework and its focus on cellular & holobiome health
  • Real-world cases that reveal the cost of treating symptoms instead of root causes
  • How medical education must evolve to create a true “standard of care for health”

This episode is for you if:

  • You’re frustrated by the limits of conventional check-ups
  • You want practical ways to apply lab data beyond “normal” reference ranges
  • You’re a practitioner ready to integrate proactive, personalized strategies
  • You believe healthspan—not just lifespan—should be the goal

You can also find this episode on…
YouTube: https://youtu.be/EMDOXr43Xg8

Find more from Smarter Not Harder:
Website: https://troscriptions.com/blogs/podcast | https://homehope.org
Instagram: @troscriptions | @homehopeorg

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