#390: Muscle, Mitophagy, and Longevity: How Urolithin A Supports Healthy Aging and Athletic Performance With Brad Currier, PhD
LONGEVITY with Nathalie Niddam
Release Date: 11/25/2025
#398: The Dopamine Biohack | Brain Chemistry, Motivation & Testosterone Secrets Revealed With Lucas Aoun
LONGEVITY with Nathalie Niddam
Today, I’m joined by , from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father’s pharmacy, to experimenting with early nootropic formulas, and ultimately becoming a sought-after educator in the world of biohacking. Episode Timestamps: Podcast introduction and guest welcome ... 00:00:00 Lucas Aoun’s journey into biohacking ... 00:04:13 Innovative supplement formulation and teacrine ... 00:10:00 Dopamine’s role in motivation and productivity ... 00:32:09 Bioindividual...
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#397: STRESS: The Silent Accelerator of Aging (10 Free Hacks Rewiring Your Longevity) | Calm Amid Chaos With Nat Niddam
LONGEVITY with Nathalie Niddam
Today, it’s just me, and we’re doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives and high-tech hacks to focus on something fundamental—free, practical strategies to help you manage stress. Chronic stress is sneaky in how it accelerates aging, impacts your telomeres, and undoes even the most powerful interventions, but thankfully, there are simple ways we can start to turn things around. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Immune...
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#396: From Trauma to Transcendence: Alpha Training, Elite Creativity Gains, and Reversing Aging — With Dr. James Hardt
LONGEVITY with Nathalie Niddam
Today, I’m joined by —founder of Biocybernaut and a true pioneer in the world of neurofeedback. With over four decades spent mapping how our brainwaves shape emotions, performance, and even identity, Dr. Hardt has helped reframe the conversation around unlocking human potential, making cutting-edge brain training accessible to seekers, creatives, and everyday biohackers alike. Download a FREE copy of his book “The Art of Smart Thinking” at Episode Timestamps: Intro to Longevity Podcast and host ... 00:00:00 Introduction to Dr. James Hardt and neurofeedback ... 00:00:34 Alpha...
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#395: Brain Fog, Anger, Detox Secrets & The Truth About Diet Sodas | Unlocking LIVER Longevity With Siggi Clavien
LONGEVITY with Nathalie Niddam
Today, I’m sitting down with the irrepressible , renowned biotech innovator and founder of , a groundbreaking formula for liver health. Siggi’s story is deeply personal—motivated by the loss of loved ones to liver disease, he’s made it his life’s mission to demystify liver health and help others avoid the fate that touched his own family. Visit code: NAT for 5% off Episode Timestamps: Introduction and podcast themes ... 00:00:00 Eastern vs. Western liver views ... 00:07:09 Why liver health is central to longevity ... 00:09:28 Hidden toxins: everyday exposures ......
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#394 How Bioregulator Peptides HALVE Mortality: Telomere Reversal, Organs REGENERATED & the 8-Year Experiment With Dr. Bill Lawrence
LONGEVITY with Nathalie Niddam
Today, I’m joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly with Professor Vladimir Khavinson—the scientist who discovered and developed bioregulator peptides—and has spent the last eight years leading some of the most exciting field research in this space. Episode Timestamps: Welcome and introduction to Longevity Podcast ... 00:00:00 Origins and early use of bioregulator peptides in Soviet research ... 00:05:39 Organ-specific peptide...
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#393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso
LONGEVITY with Nathalie Niddam
Today, I'm joined by the incomparable —a true pioneer in shifting healthcare from “what’s wrong with you” to “what’s right with you.” Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can’t ignore, and how something as simple as a toxicity panel can completely change your health trajectory. Episode Timestamps: Welcome and episode introduction ......
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#392: Biohacking the MIND: 78% Anxiety Remission, Vagus Nerve Secrets & The Mental Health Revolution | Zenbud’s Jon Hacker Unlocks REST
LONGEVITY with Nathalie Niddam
Today, I’m joined by the innovative , whose name couldn’t be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mind. After growing up with severe OCD and witnessing the rising tide of global anxiety, he became obsessed with one question: Why are we all stuck in fight or flight, and what can we actually do about it? Use code NAT at for 15% off Episode Timestamps: Introduction to Longevity Podcast and Host ... 00:00:00 The Rise of Anxiety and Mental Health Innovation ... 00:05:19 Why Modern Society...
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#391: Unlocking SCALP Health: The Biohack That Will Change Your Hair Forever With Nadine Artemis
LONGEVITY with Nathalie Niddam
Today, I’m joined by the incredible , a true pioneer in natural beauty and holistic health. Nadine is well known for bridging the gap between ancient wisdom and modern science, and in this episode, she completely redefines how we look at hair care—not just as a cosmetic routine, but as a form of biological reset. She shares how everything from stress to toxins and even your shower water can disrupt the delicate ecosystem of your scalp, and how her simple, nature-inspired rituals can help restore balance. Past episode: Study with Rosemary: Episode Timestamps:...
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#390: Muscle, Mitophagy, and Longevity: How Urolithin A Supports Healthy Aging and Athletic Performance With Brad Currier, PhD
LONGEVITY with Nathalie Niddam
Today, I’m joined by Dr. Brad Currier, Manager of Clinical Trials at and an expert in the world of muscle and aging research. Brad is on the cutting edge of mitochondrial science, and in this episode, he helps us unravel the mysteries of why some 80-year-olds are still crushing it in the gym while others struggle to get up the stairs. We dive into his fascinating research on mitophagy—our bodies’ system for recycling dysfunctional mitochondria—and what it means for muscle health, strength, and vibrant aging. Visit and use code nat20 for 20% off your purchase. Episode...
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#389: How Migraines, Mitochondria Dysfunction, and Modern Lifestyles Impact Brain Health and Aging With Elena Gross
LONGEVITY with Nathalie Niddam
Today, I’m joined by the brilliant , a neuroscientist with an inspiring story and a relentless drive to solve the mysteries behind chronic migraines and brain health. Dr. Gross’s personal journey—enduring twenty days of migraine each month and navigating countless failed treatments—led her from crawling through the pain to founding Brain Ritual, a company reimagining brain fuel for longevity. Episode Timestamps: Intro and offers ... 00:00:00 Elena Gross’s journey from chronic migraines to neuroscience ... 00:46 Distinguishing migraines from headaches ... 08:13 Energy deficit...
info_outlineToday, I’m joined by Dr. Brad Currier, Manager of Clinical Trials at Timeline Nutrition and an expert in the world of muscle and aging research. Brad is on the cutting edge of mitochondrial science, and in this episode, he helps us unravel the mysteries of why some 80-year-olds are still crushing it in the gym while others struggle to get up the stairs. We dive into his fascinating research on mitophagy—our bodies’ system for recycling dysfunctional mitochondria—and what it means for muscle health, strength, and vibrant aging.
Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase.
Episode Timestamps:
Episode start … 00:00:00
What is Mitophagy? Why It Matters as We Age ... 00:04:53
Mitophagy in Athletes vs. General Population ... 00:07:15
Urolithin A and Why Most People Can’t Make It ... 00:12:12
What Mitopure Does: Mitophagy and Biogenesis ... 00:24:10
Key Study: Strength Gains in Middle-Aged Adults ... 00:26:43
Dose Guidance: 500mg vs. 1g ... 00:31:39
Anti-Inflammatory Effects and Immune Health ... 00:33:07
Benefits Beyond Muscle: Skin, Immunity, Brain ... 00:35:01
Weightlifter Study: Performance in Trained Athletes ... 00:40:34
Mitopure for Recovery and User Experiences ... 00:46:41
How to Use Mitopure: Timing, Dosage, Consistency ... 00:52:54
Protein, Creatine, and Mitopure: The Basics Stack ... 00:53:41
Recovery, Cycling, and How Soon Benefits Appear ... 00:58:44
Debunking Myths: Pomegranate, Antioxidant, Athletes Only ... 01:10:26
Mitopure vs. Generic Urolithin A: Safety Concerns ... 01:13:39
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