876 - The Science of Leaky Gut with Dr Michael Camilleri MD (Mayo Clinic)
Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
Release Date: 01/22/2024
Dr. Ruscio Radio, DC: Health, Nutrition and Functional Healthcare
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info_outlineThere’s still a lot we don’t understand about the science of leaky gut. Does it cause disease or is it a symptom? What’s the best way to test for it? Which treatments actually work to repair it?
Today’s guest is one of the best people to begin to answer these questions.
Dr. Camilleri is a renowned gastroenterology researcher and professor at the Mayo Clinic.
Tune in to hear about cutting-edge innovations and informed understandings around leaky gut testing and treatment.
If you have any additional questions you would like answered in the future, let me know in the comments!
Watch/Read Next…
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What is Leaky Gut: https://drruscio.com/what-is-leaky-gut/
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Leaky Gut Suplements: https://drruscio.com/leaky-gut-supplements/
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Probiotics for Stomach Issues: https://drruscio.com/probiotics-for-stomach
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Learn more about Dr. Camilleri’s work: https://www.mayo.edu/research/faculty/camilleri-michael-m-d-d-sc/bio-00026245
Timestamps
00:00 Intro
03:25 Dr. Camilleri’s background with leaky gut
05:05 Bile-acid supplementation
07:20 The small intestine
11:07 The prevalence of leaky gut
14:25 Leaky gut & diseases
20:08 Leaky gut & inflammation
30:18 Treatment: Where to start
36:09 Biomarkers of leaky gut
48:53 Leaky gut testing
53:24 Gluten intolerance prevalence
59:52 Food elimination & reintroduction
01:04:47 Prebiotics & FODMAPs
01:15:26 Probiotics
Featured Studies
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What to do about the leaky gut: https://pubmed.ncbi.nlm.nih.gov/34509978/
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Leaky gut: mechanisms, measurement and clinical implications in humans: https://pubmed.ncbi.nlm.nih.gov/31076401/
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Development and Validation of Test for "Leaky Gut" Small Intestinal and Colonic Permeability Using Sugars in Healthy Adults: https://pubmed.ncbi.nlm.nih.gov/33865841/
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A case for improved assessment of gut permeability: a meta-analysis quantifying the lactulose:mannitol ratio in coeliac and Crohn's disease: https://pubmed.ncbi.nlm.nih.gov/35012471/
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Food Emulsifiers and Metabolic Syndrome: The Role of the Gut Microbiota: https://pubmed.ncbi.nlm.nih.gov/35892789/
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Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease: https://pubmed.ncbi.nlm.nih.gov/33336247/
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Serum zonulin and its diagnostic performance in non-coeliac gluten sensitivity: https://pubmed.ncbi.nlm.nih.gov/32060130/
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Psychological and Gastrointestinal Symptoms of Patients with Irritable Bowel Syndrome Undergoing a Low-FODMAP Diet: The Role of the Intestinal Barrier: https://pubmed.ncbi.nlm.nih.gov/34371976/
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Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials: https://pubmed.ncbi.nlm.nih.gov/37168869/
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Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome: https://pubmed.ncbi.nlm.nih.gov/30108163/
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Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g
*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.