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EFR 891: Nitric Oxide Explained - Dr. Nathan Bryan on Aging, Alzheimer’s, and Performance

Ever Forward Radio with Chase Chewning

Release Date: 08/11/2025

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More Episodes

Nitric oxide might be the most important molecule you’ve never heard of. In this episode, molecular medicine pioneer Dr. Nathan Bryan, PhD reveals how this fleeting gas controls blood flow, brain health, immune defense, and even sexual function. We cover the science of nitric oxide, how lifestyle choices impact its production, and why it could hold the key to preventing age-related diseases like Alzheimer’s. You’ll learn simple daily strategies to boost your nitric oxide naturally—without falling for supplement marketing gimmicks.

Follow Dr. Bryan @drnathansbryan

Follow Chase @chase_chewning

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In this episode we discuss...

00:00 – Introduction

01:00 – What is Nitric Oxide?

03:05 – Why Nitric Oxide is Short-Lived

05:34 – How Nitric Oxide Works

08:03 – Immune Defense & Nitric Oxide

09:50 – Symptoms of Low Nitric Oxide

15:11 – The American Lifestyle Problem

19:56 – Nitric Oxide for Performance & Recovery

24:06 – Cardiovascular Health & Longevity

26:03 – How the Body Produces Nitric Oxide

32:00 – Beetroot & Supplement Myths

34:04 – Two Steps to Boost Production

36:03 – Nasal Breathing & Humming

39:01 – Mouth Taping for Sleep & Nitric Oxide

41:52 – Oral Microbiome & Diet

44:46 – The Antacid Problem

49:40 – Variability in Vegetable Nitrate Levels

52:52 – Risks of Overproduction

54:40 – Nitrate/Nitrite Marketing Myths

58:34 – Cutting-Edge Research & Drug Development

01:03:08 – Dr. Bryan’s Daily Optimization Protocol

01:07:52 – The Mindset of Doing Hard Things

01:10:38 – Ever Forward

01:11:44 – Nitric Oxide & ALS

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