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308: Fasting, Nicotine, and Microdosing LSD for Optimal Health Ft Sean McCormick

Get Leaner & Live Longer

Release Date: 08/11/2025

326: The Power of Psychedelics in Creating Lasting Change Ft Austin Mao show art 326: The Power of Psychedelics in Creating Lasting Change Ft Austin Mao

Get Leaner & Live Longer

If you want to get leaner and live longer check out   Have you ever wondered if psychedelics could unlock better mental health, emotional intelligence, or a deeper connection with yourself and others?   I talk with Austin Mao, who is a licensed natural medicine facilitator and co-founder of Ceremonia, a legal psychedelic center in Denver, Colorado. Austin is the Program Director & Head Minister and has guided over 500 individuals. We discuss the purpose of using guided psilocybin and ayahuasca experiences to foster profound healing and personal growth. Austin explains that...

info_outline 325: Optimize Your Sleep Performance to Improve Energy, Fat Loss, & Recovery show art 325: Optimize Your Sleep Performance to Improve Energy, Fat Loss, & Recovery

Get Leaner & Live Longer

If you want to get leaner and live longer check out   Why do we spend thousands on workouts and supplements, but treat sleep like an afterthought, and how is it hurting our performance?   I talk with Jill MacRae and Lori Oliver, co-founders of The Inactive Company, a sleep performance business focused on developing products and technology. They brought complementary expertise from companies like SPANX, Starbucks, and Coca-Cola to solve the sleep epidemic. We discuss how they moved past their own sleep struggles—Jill with staying asleep, Lori with falling asleep in a constant...

info_outline 324: AI Based Longevity Ft. Hunter Ziesing show art 324: AI Based Longevity Ft. Hunter Ziesing

Get Leaner & Live Longer

If you want to get leaner and live longer check out   Will an AI doctor soon replace your physician? I talk about how personalized testing and artificial intelligence are making true preventative health cheaper and more accessible.   I talked with Hunter Ziesing, who shifted from a successful career in finance after losing family and friends to preventable diseases. He now runs Longevity Health, a virtual clinic providing comprehensive diagnostic testing, including 60 blood biomarkers, DEXA scans, and VO2 max, for $11,000 annually. The goal is to make health preventative, not...

info_outline 323: How Chris Reade Reversed His Diabetes show art 323: How Chris Reade Reversed His Diabetes

Get Leaner & Live Longer

If you want to get leaner and live longer check out   Is diabetes truly a life sentence, or can you reverse it without relying on drugs like Metformin or Ozempic?   I talked with Chris Reade, who discovered a serious health condition after a life insurance exam. His A1C went from normal to a high 9.1 in 10 months because of visceral fat around his pancreas. Doctors told him this disease was progressive and incurable, but Chris refused that sentence. He researched and found a simple strategy focused on using soluble fiber to control blood sugar spikes. This method forces weight loss...

info_outline 322: 4 Tips to Get Through the Holidays Fitter Instead of Fatter show art 322: 4 Tips to Get Through the Holidays Fitter Instead of Fatter

Get Leaner & Live Longer

If you want to get leaner and live longer check out Most people don’t get derailed during the holidays because of Thanksgiving or Christmas dinner. They get derailed because of the tiny, constant “it’s only one” decisions that stack up every day for six straight weeks. In this episode, Nate breaks down the four levers that keep you in control, protect your energy, and prevent holiday backsliding so you can hit January feeling strong instead of defeated. What You’ll Learn: • Why the “big meals” aren’t the real problem — the micro-decisions are • How installing...

info_outline 321: Healthy & Wealthy Longevity? Ft. Jon Sabes show art 321: Healthy & Wealthy Longevity? Ft. Jon Sabes

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If you want to get leaner and live longer check out   How can you leverage positive thinking and simple lifestyle habits to change your biological age by a decade?   In this episode, I talked with Jon Sabes, a longevity researcher and entrepreneur. He has worked with biomarkers of aging and health for the life insurance industry. Jon shares how his mother's passing shaped his book, Healthy Wealthy Longevity. I learned about the connection between positive thinking, physical activity, and gene expression through epigenetics. We discussed the importance of mastering the basics: eating...

info_outline 320: The N=1 Experiment That Can Change Everything show art 320: The N=1 Experiment That Can Change Everything

Get Leaner & Live Longer

You don’t need another diet plan or “perfect” fitness routine — you need curiosity. In this episode, Nate reveals how running N=1 experiments (small, personal tests) can help you finally break out of copy-paste fitness and start getting results that actually fit your body and lifestyle. You’ll learn how to test what works for you without overcomplicating things — whether that’s shifting your meal timing, adjusting your workouts, or simply paying attention to how your body feels. By the end, you’ll know exactly how to stop guessing and start discovering what helps you feel...

info_outline 319: How to Live Forever Ft Dr Bill Andrews show art 319: How to Live Forever Ft Dr Bill Andrews

Get Leaner & Live Longer

If you want to get leaner and live longer check out    Why do our bodies slowly break down, even if we eat right and exercise? We dive deep into the biological switch at the cellular level that determines human longevity.   I spoke with Dr. Bill Andrews, the father of telomere biology and a co-discoverer of telomerase. He explained why aging happens: telomeres, the protective caps on our DNA, shorten every time a cell divides, acting like a cellular clock. We talked about an obsession with curing aging. We discussed methods to re-lengthen telomeres, primarily using plant...

info_outline 318: No Sugar No Grains for Fast Fat Loss? Ft. Vinnie Totorich show art 318: No Sugar No Grains for Fast Fat Loss? Ft. Vinnie Totorich

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Have you ever wondered why nutrition seems so complicated, with constantly changing dietary advice, making it hard to know what's truly healthy? I speak with Vinnie Tortorich, a celebrity trainer and author, about cutting through nutrition noise. We discuss how the food industry feeds people untruths, shaping the obesity and chronic disease epidemic. Vinnie, who created the No Sugar, No Grains movement (NSNG), explains that celebrities achieve results through high levels of dedication. We explore why people must sacrifice for goals and how success requires facing failure and maintaining...

info_outline 317: The Hidden Key to Building Muscle and Burning Fat at the Same Time show art 317: The Hidden Key to Building Muscle and Burning Fat at the Same Time

Get Leaner & Live Longer

Most people think they know what to do to get in shape — they just aren’t doing it. But what if what you “knew” wasn’t actually true? In this episode, Nate Palmer pulls back the curtain on one of the biggest myths in fitness: that you have to choose between building muscle and losing fat. You’ll learn why most programs sabotage results by raising stress and depleting energy — and how small, smart shifts can make your body want to change. Nate reveals the 3 hidden pillars behind predictable body recomposition: Top End Failure Training — how to trigger...

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More Episodes

Have you ever considered dry fasting for five days to regenerate your body, or using a pendulum to shift energy and reduce pain? I'm sharing some wild ideas today.

I talked with Sean McCormick, host of the Optimal Performance podcast and a human guinea pig for health experiments. We discussed the kettlebell mile, a test of strength and endurance, and how grip strength predicts longevity. Sean shared insights on nicotine as a neuroprotectant and its effects. We explored the deep benefits of dry fasting, including muscle preservation and fat loss. Sean also described using a pendulum to harmonize energy and reduce pain. He shared his experiences with mini-dosing LSD for creativity and focus. I learned about the importance of N of one experiments for personal health journeys.

Key takeaways

  • Grip strength is an indicator of longevity, and tests like the kettlebell mile assess both strength and aerobic capacity.

  • A dopamine detox protocol can help reset your body and mental clarity.

  • Dry fasting for multiple days (without food or water) can regenerate the body on a cellular level, preserve muscle, and lead to significant fat loss, reaching deep ketosis and stem cell activation.

  • Nicotine has potential benefits as a neuroprotectant, nootropic, and may offer anti-bacterial or anti-parasitic properties, but it can be addictive and is a vasoconstrictor.

  • Oral TRT offers a different approach to testosterone replacement by providing mini-doses that may not hijack natural production.

  • Herbal supplements, like dried ants, are used in traditional practices for physical strength.

  • Pendulums made of magnetic metals can be used in energy medicine to harmonize energetic points, transmute negative energies, and potentially reduce pain.

  • Microdosing or mini-dosing psychedelics like LSD or psilocybin can enhance creativity, focus, and offer anti-inflammatory effects, and can improve cognition.

  • Conducting "N of one" experiments is a critical and fun way to learn about your own body's response to different health and fitness protocols.

Resources

 

The founder of The Million Dollar Body and author of "The Million Dollar Body Method", Nate has been coaching for over 15 years and has worked personally with over 1,000 clients.