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308: Fasting, Nicotine, and Microdosing LSD for Optimal Health Ft Sean McCormick

Get Leaner & Live Longer

Release Date: 08/11/2025

331: Did You Miss Your Fitness Window? What a 47-Year Study Actually Says About Staying Fit for Life show art 331: Did You Miss Your Fitness Window? What a 47-Year Study Actually Says About Staying Fit for Life

Get Leaner & Live Longer

If you want to get leaner and live longer, go to Milliondollarbodylabs.com A new 47-year longitudinal study is making the rounds with a scary takeaway: if you weren’t fit in your 30s, you’re basically out of luck later in life. That interpretation is wrong, incomplete, and lazy. In this episode, we break down what the study actually tracked, what it really tells us about human performance over time, and why fitness is better understood as a trajectory problem, not a deadline problem. We talk about how aerobic capacity, strength, and power tend to peak earlier in life, why that early peak...

info_outline 330: Coaching World Class Athletes Ft Jay Pages show art 330: Coaching World Class Athletes Ft Jay Pages

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If you want to get leaner and live longer check out   Why do most people quit right before they achieve mastery, and how can you build leadership that lasts decades through small, unsexy reps every single day?   I talk with Jay Pages. He owns a gym in Arizona. He describes leaving his career as an officer of loans during a bubble burst to coach. We discuss leadership from the top down and the need for action over words. He explains the journey to a belt and how mastery starts after a decade of practice. We explore the use of games to build skills and how resistance improves...

info_outline 329: Fitness Is Growing Up show art 329: Fitness Is Growing Up

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If you want to get leaner and live longer check out https://milliondollarbodylabs.com   Fitness is growing up. The people getting leaner and staying healthy aren’t doing extreme programs, chasing novelty, or training like competitors. They’re building capacity, regulating stress, and removing friction. In this episode, we break down the real fitness trends heading into 2026 based on research, behavior shifts, and what successful people are actually doing. No hype. No hacks. Just what works. What You’ll Learn in This Episode • Why fitness is shifting from aesthetics to metabolic...

info_outline 328: DO SOME REPS RIGHT TF NOW Ft. Donovan Owens show art 328: DO SOME REPS RIGHT TF NOW Ft. Donovan Owens

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If you want to get leaner and live longer check out   Are you tired of chasing big fitness goals only to fail once the wedding or vacation is over? What if the secret to lasting success is found in being "boring"?   I talk with Donovan Owens about his "Life is Reps" philosophy. He retired from owning fitness businesses to focus on mastery and presence. We discuss how big gestures like extreme diets usually fail because identity remains the same. Donovan explains his mastery morning system which includes physical, mental, and spiritual wins before interacting with anyone. He...

info_outline 327: What Actually Mattered This Year show art 327: What Actually Mattered This Year

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This isn’t a highlight reel. It’s an audit. Instead of recapping guests or episodes, this end of year review distills the ideas that kept surfacing across the most listened to conversations of 2025. Different topics. Same underlying problems. In this episode, we break down what actually mattered this year when it came to fat loss, energy, discipline, gut health, cravings, recovery, and long term health. What We Cover • Why energy dictates consistency more than willpower • The real reason discipline feels restrictive for most people • How chronic stress quietly drives belly fat and...

info_outline 326: The Power of Psychedelics in Creating Lasting Change Ft Austin Mao show art 326: The Power of Psychedelics in Creating Lasting Change Ft Austin Mao

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If you want to get leaner and live longer check out   Have you ever wondered if psychedelics could unlock better mental health, emotional intelligence, or a deeper connection with yourself and others?   I talk with Austin Mao, who is a licensed natural medicine facilitator and co-founder of Ceremonia, a legal psychedelic center in Denver, Colorado. Austin is the Program Director & Head Minister and has guided over 500 individuals. We discuss the purpose of using guided psilocybin and ayahuasca experiences to foster profound healing and personal growth. Austin explains that...

info_outline 325: Optimize Your Sleep Performance to Improve Energy, Fat Loss, & Recovery show art 325: Optimize Your Sleep Performance to Improve Energy, Fat Loss, & Recovery

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If you want to get leaner and live longer check out   Why do we spend thousands on workouts and supplements, but treat sleep like an afterthought, and how is it hurting our performance?   I talk with Jill MacRae and Lori Oliver, co-founders of The Inactive Company, a sleep performance business focused on developing products and technology. They brought complementary expertise from companies like SPANX, Starbucks, and Coca-Cola to solve the sleep epidemic. We discuss how they moved past their own sleep struggles—Jill with staying asleep, Lori with falling asleep in a constant...

info_outline 324: AI Based Longevity Ft. Hunter Ziesing show art 324: AI Based Longevity Ft. Hunter Ziesing

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If you want to get leaner and live longer check out   Will an AI doctor soon replace your physician? I talk about how personalized testing and artificial intelligence are making true preventative health cheaper and more accessible.   I talked with Hunter Ziesing, who shifted from a successful career in finance after losing family and friends to preventable diseases. He now runs Longevity Health, a virtual clinic providing comprehensive diagnostic testing, including 60 blood biomarkers, DEXA scans, and VO2 max, for $11,000 annually. The goal is to make health preventative, not...

info_outline 323: How Chris Reade Reversed His Diabetes show art 323: How Chris Reade Reversed His Diabetes

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If you want to get leaner and live longer check out   Is diabetes truly a life sentence, or can you reverse it without relying on drugs like Metformin or Ozempic?   I talked with Chris Reade, who discovered a serious health condition after a life insurance exam. His A1C went from normal to a high 9.1 in 10 months because of visceral fat around his pancreas. Doctors told him this disease was progressive and incurable, but Chris refused that sentence. He researched and found a simple strategy focused on using soluble fiber to control blood sugar spikes. This method forces weight loss...

info_outline 322: 4 Tips to Get Through the Holidays Fitter Instead of Fatter show art 322: 4 Tips to Get Through the Holidays Fitter Instead of Fatter

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If you want to get leaner and live longer check out Most people don’t get derailed during the holidays because of Thanksgiving or Christmas dinner. They get derailed because of the tiny, constant “it’s only one” decisions that stack up every day for six straight weeks. In this episode, Nate breaks down the four levers that keep you in control, protect your energy, and prevent holiday backsliding so you can hit January feeling strong instead of defeated. What You’ll Learn: • Why the “big meals” aren’t the real problem — the micro-decisions are • How installing...

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More Episodes

Have you ever considered dry fasting for five days to regenerate your body, or using a pendulum to shift energy and reduce pain? I'm sharing some wild ideas today.

I talked with Sean McCormick, host of the Optimal Performance podcast and a human guinea pig for health experiments. We discussed the kettlebell mile, a test of strength and endurance, and how grip strength predicts longevity. Sean shared insights on nicotine as a neuroprotectant and its effects. We explored the deep benefits of dry fasting, including muscle preservation and fat loss. Sean also described using a pendulum to harmonize energy and reduce pain. He shared his experiences with mini-dosing LSD for creativity and focus. I learned about the importance of N of one experiments for personal health journeys.

Key takeaways

  • Grip strength is an indicator of longevity, and tests like the kettlebell mile assess both strength and aerobic capacity.

  • A dopamine detox protocol can help reset your body and mental clarity.

  • Dry fasting for multiple days (without food or water) can regenerate the body on a cellular level, preserve muscle, and lead to significant fat loss, reaching deep ketosis and stem cell activation.

  • Nicotine has potential benefits as a neuroprotectant, nootropic, and may offer anti-bacterial or anti-parasitic properties, but it can be addictive and is a vasoconstrictor.

  • Oral TRT offers a different approach to testosterone replacement by providing mini-doses that may not hijack natural production.

  • Herbal supplements, like dried ants, are used in traditional practices for physical strength.

  • Pendulums made of magnetic metals can be used in energy medicine to harmonize energetic points, transmute negative energies, and potentially reduce pain.

  • Microdosing or mini-dosing psychedelics like LSD or psilocybin can enhance creativity, focus, and offer anti-inflammatory effects, and can improve cognition.

  • Conducting "N of one" experiments is a critical and fun way to learn about your own body's response to different health and fitness protocols.

Resources

 

The founder of The Million Dollar Body and author of "The Million Dollar Body Method", Nate has been coaching for over 15 years and has worked personally with over 1,000 clients.