Revolutionizing ALS Treatment: The Tofersen Breakthrough
Release Date: 03/17/2025
Neurology® Podcast
The February 2026 recall features four previously posted episodes on multiple sclerosis. The episode begins with a conversation with Dr. Wallace J. Brownle discussing whether dissemination in time is essential to diagnois relapsing MS. The discussion continues with Dr. Daniel Ontaneda regarding the 2024 revisions of the McDonald criteria for diagnosing multiple sclerosis. The episode then transitions into a conversation with Dr. Jiwon Oh about BTK inhibitors and recent data on tolebrutinib in multiple sclerosis. The episode concludes with Dr. Sandra Vukusic addressing the differences in...
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Dr. Tesha Monteith talks with Dr. Michael Eller about the implications of CGRP therapies in migraine treatment, particularly for patients with vascular risk factors or a history of stroke. Read the related article in . Disclosures can be found at .
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Dr. Stacey Clardy talks with Dr. John Ney about the prevalence, disability burden, and societal impact of neurologic disorders in the U.S. Read the related article in . Disclosures can be found at .
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In the second episode of this two-part series, Dr. Justin Abbatemarco talks with Drs. Valérie Biousse and Nancy J. Newman about the management of non-arteritic ischemic optic neuropathy and its emerging relationship with GLP‑1 medications. Disclosures can be found at .
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In part one of this two-part series, Dr. Justin Abbatemarco talks with Drs. Valérie Biousse and Nancy J. Newman about the clinical features and diagnostic tools utilized for non-arteritic ischemic optic neuropathy (NAION). Disclosures can be found at .
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Dr. Justin Abbatemarco talks with Dr. Divyanshu Dubey about how antibodies to synaptophysin and GAP43 help explain an autoimmune neuropathy seen in swine abattoir workers and offer new clues for diagnosing and treating related inflammatory neuropathies. Read the related article in . Disclosures can be found at .
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In the second installment of this two-part series, Dr. Stacey Clardy talks with Drs. Ayush Gupta and Kuntal Sen about the spinal cord and optic neuritis, while outlining practical approaches to genetic testing and emphasizing the importance of collaboration with genetic counselors and neurogeneticists. Read the related article in Genetics. Disclosures can be found at .
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In part one of this two-part series, Dr. Stacey Clardy talks with Drs. Ayush Gupta and Kuntal Sen about the phenotypes commonly seen in CNS inflammatory and demyelinating diseases, and discuss genetic conditions in patients who do not precisely meet classic diagnostic criteria. Read the related article in Genetics. Disclosures can be found at .
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Dr. Elizabeth Coon talks with Prof. Franziska Hopfner about the frequency and disease trajectory of MSA patients who do not experience dysautonomia, in comparison to those with autonomic involvement. Read the related article in . Disclosures can be found at .
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Start the new year with the January 2026 Recall, featuring five episodes focused on the topic of AI in neurology. The episode begins with Dr. Stacey Clardy talking with Stephen Marche about the evolving topic of natural language processing and its impact on neurology and everyday life. The episode leads into a conversation with Drs. Halley Alexander and Sándor Beniczky discussing the use of AI to accurately interpret routine clinical EEG. The conversation continues with Drs. Trey Bateman and David T. Jones discussing the use of FDG-PET imaging and machine learning to improve diagnostic...
info_outlineDr. Gordon Smith talks with Dr. Timothy Miller about compelling patient stories and clinical data that highlight the potential for recovery in ALS patients, emphasizing the importance of early intervention and understanding the disease mechanisms.
Disclosures can be found at Neurology.org.