Episode 409: An Overview of Interventional Oncology for Nurses
Release Date: 04/03/2026
The ONS Podcast
“We thought, from a nursing standpoint, ‘What is our goal for doing this?’ What we wanted was first, education of the patient. Can we successfully educate the patient to prepare them? Can we alleviate as much anxiety as possible so that they feel comfortable coming in and having this done? The second goal is to preserve kidney function throughout the treatment. To date, we’ve been successful with that. And the third goal is to complete treatment without infection,” ONS member Chris Amoroso, BSN, RN, OCN®, registered nurse at Fox Chase Cancer Center in Philadelphia, PA, told Jaime...
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“They are small, powerful little nuggets. They are actually small signaling proteins that our immune cells use to communicate. They really help regulate immune activation or inflammation and even the growth and survival of immune cells. When cytokines are used therapeutically in oncology, they help to stimulate immune cells such as T cells or natural killer cells to better recognize and attack cancer cells,” Maribel Pereiras, PharmD, BCPS, BCOP, clinical pharmacy specialist at the John Theurer Cancer Center of Hackensack University Medical Center in New Jersey, told Jaime Weimer, MSN,...
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“Not every patient with myelodysplastic syndrome (MDS) is going to progress and die. Only 10%–20% of them will evolve into acute myeloid leukemia. And not all of them need blood transfusions. Some present with low platelet count. It’s not just people who are anemic that have MDS—it’s different depending on what type of MDS they have. These are averages. We’re giving you statistics based on averages, and you’re an individual, so we want to treat you as an individual,” ONS member Sara Tinsley-Vance, PhD, APRN, AOCN®, nurse practitioner and quality-of-life researcher at Moffitt...
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“Cancer and environmental disasters in particular, but the worsening of our environment, are really things that are great equalizers. And we recognize that we’re all kind of in this world together. We can really face these issues on a more human level. I think always recognizing that if we look at something, we think, ‘Well, that doesn’t relate to me or that problem is it really isn’t my problem’—it sure is,” ONS member Margaret “Peggy” Rosenzweig, PhD, CRNP-C, AOCNP®, FAAN, ONS scholar-in-residence and distinguished service professor of nursing and Nancy Glunt Hoffman...
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“Interventional oncology has really evolved into an important component of modern cancer care and is often described now as the fourth pillar alongside medical, surgical, and radiation oncology. The specialty now encompasses a broad spectrum of image-guided procedures that support from cancer diagnosis, treatment, to effectively managing symptoms that are caused by the disease. In other words, what we’re seeing is that across the continuum of care, IO is playing a vital role,” ONS member Evelyn P. Wempe, DNP, MBA, APRN, ACNP-BC, AOCNP®, CRN, NEA-BC, executive director for advanced...
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“A side effect patients might experience is lymphedema. This is an increased buildup of lymphatic fluid in the tissues, either in the breast or in the arm and hand of the affected side. It’s quite problematic for women. They might feel self-conscious. It might feel uncomfortable that the arm feels like it’s throbbing or heavy. Clothing may not fit quite right. So we’re always on the lookout for lymphedema,” Maria Fenton-Kerimian, APRN, AOCNP®, nurse practitioner at Weill Cornell Medicine in New York, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice...
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“You want to try to act quickly and be able to know what the pathways are for appropriate escalating when a patient is having symptoms that are reflective of cytokine release syndrome (CRS) or neurotoxicity. These toxicities are very manageable and treatable when recognized early. To summarize, choosing the right patient, knowing the toxicity profile for each product, and acting early is really what helps to prevent severe outcomes with chimeric antigen receptor (CAR) T-cell therapy,” Maribel Pereiras, PharmD, BCPS, BCOP, clinical pharmacy specialist at the John Theurer Cancer Center at...
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“Our goal of precision oncology has been to shift to tailored therapies that can help to improve treatment efficacy and ultimately improve patient outcomes. Resistance biomarker testing can help the care team to detect these genomic changes that the tumor may have acquired during therapy that makes the cells resistant to therapy. This information can be extremely helpful when we’re talking about making choices about second-line or subsequent-line therapy,” ONS member Danielle Fournier, DNP, APRN, AGPCNP-BC, AOCNP®, advanced practice RN at the University of Texas MD Anderson Cancer...
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“The disease is increasingly managed as a chronic condition rather than a diagnosis with an immediate terminal outcome. Particularly, with earlier and more effective and sustained treatment options, we can make this disease a very chronic, long-term, livable condition. I want to make sure that patients are aware that this is not a death sentence. This is something that patients can live with for the long term,” Ann McNeill, RN, MSN, APN, nurse practitioner at the John Theurer Cancer Center at Jersey Shore University Medical Center in Neptune, NJ, told Lenise Taylor, MN, RN, AOCNS®,...
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“We print education sheets that we have, and we say, ‘Just ignore this part that says cancer. You’re getting this med but for a different indication.’ And then you have to really point out what our goals of care are. You’re using the information that, as oncology nurses, we like and love, but we’re having to cross it out and say, ‘Just read this portion and just do this here.’ And that can be challenging for the nurse and probably confusing for the patient,” ONS member Brandy Thornberry, RN, OCN®, outpatient infusion and VAD supervisor at Logan Health in Kalispell, MT,...
info_outline“Interventional oncology has really evolved into an important component of modern cancer care and is often described now as the fourth pillar alongside medical, surgical, and radiation oncology. The specialty now encompasses a broad spectrum of image-guided procedures that support from cancer diagnosis, treatment, to effectively managing symptoms that are caused by the disease. In other words, what we’re seeing is that across the continuum of care, IO is playing a vital role,” ONS member Evelyn P. Wempe, DNP, MBA, APRN, ACNP-BC, AOCNP®, CRN, NEA-BC, executive director for advanced practice providers for the oncology service line at the University of Miami Sylvester Comprehensive Cancer Center in Florida, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about interventional oncology.
Music Credit: “Fireflies and Stardust” by Kevin MacLeod
Licensed under Creative Commons by Attribution 3.0
Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by April 3, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.
Learning outcome: Learners will report an increase in knowledge related to interventional oncology as a treatment modality for cancer.
Episode Notes
- Complete this evaluation for free NCPD.
- ONS Podcast™ episodes:
- Episode 347: Care Considerations for Radiopharmaceuticals and Theranostics in Patients With Cancer
- Episode 285: Transarterial Chemoembolization: The Oncology Nurse’s Role
- ONS Voice articles:
- Advancements in Interventional Oncology Ease Pain and Limit Opioid Use
- Build Your Confidence in Understanding Vascular IO Procedures
- From Heat to Cold to Electrical Pulses, Here’s How Percutaneous IO Can Preserve Life and Function
- Interventional Oncology Is an Evolving Subspecialty for Oncology Nurses
- Clinical Journal of Oncology Nursing articles:
- Interventional Oncology (December 2025 supplement)
- Expanding the Scope: The Emergence of Interventional Oncology Nursing
- The Evolution of Interventional Oncology and the Specialized Role of Oncology Nursing
- Interventional Oncology Learning Library
- Interventional Oncology Huddle Card
- Society of Interventional Oncology
- Association for Radiologic and Imaging Nursing
- Society of Interventional Radiology: Cancer resources
- RadiologyInfo.org (Radiological Society of North America)
To discuss the information in this episode with other oncology nurses, visit the ONS Communities.
To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library.
To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org.
Highlights From This Episode
“In the 1990s, tumor-focused procedures such as embolization and ablation began to emerge, marking a shift toward oncologic applications. The 2000s saw rapid technologic advancements that expanded the scope and volume of oncology-directed interventions, including vascular access device placement, liver-directed transcatheter therapies for tumor control, and more sophisticated ablation modalities. Today, interventional oncology, or IO, extends beyond procedural work, encompassing comprehensive clinical care through dedicated IO clinics that support patient consultations, treatment planning, and postprocedure follow-up.” TS 1:50
“In the immediate postprocedure phase, the IO nurse plays a critical role in patient safety in education, and oftentimes it may not be the same nurse that’s caring for the patient in the procedural environment versus the postprocedural environment. But the role is really about continuous need to assess the patient’s comfort level, to ensure that there is hemodynamic stability of the patient while closely monitoring for complications such as bleeding at the access site—of course, depending on the procedure—if there’s any hematoma formation or changes in vital signs, or if there’s any pain that needs to be addressed. Most importantly is maintaining patient safety in that immediate phase after the procedure.” TS 8:07
“Before an IO procedure, both teams really must review the patient’s clinical status. There has to be a clear understanding of: Is this patient ready to undergo a procedure? Is there any necessary imaging that needs to be done, as well as laboratory review and any systemic treatments, that may affect procedural planning? And oftentimes, in my experience, really, the oncology nurses are the ones really speaking with each other based on what the decision has been from both teams working together and communicating this to the patient.” TS 13:49
“I think the oncology nurse needs to assess the patient’s baseline understanding of interventional oncology. I often began my visits with a simple, open-ended question, ‘Tell me why you’re here today.’ This allowed me to gauge their knowledge of the specialty and the purpose of the visit with the IO team. And in many cases, patients were unfamiliar with interventional oncology, which meant education needed to start with an explanation of what IO is and how it fits into their cancer care journey. Once that foundation was established, I was then able to introduce information about the specific procedure and its role in their overall treatment plan. And we can work together to establish goals of care and health. Having this approach ensured patients were informed, engaged, and better prepared for the procedure ahead.” TS 16:06
“As nurses explore career options, interventional oncology is definitely one to consider. It really unites technology and innovation, and I think that’s where we’re heading with health care, with so much advancement in research and science. There’s definitely a place for oncology nurses in this space, and it would be great to see that continue to flourish.” TS 24:23