Episode 74: Outcomes for CTEPH patients with High Antiphospholipid Antibodies after Pulmonary Endarterectomy
Release Date: 12/17/2025
Episode 74: Outcomes for CTEPH patients with High Antiphospholipid Antibodies after Pulmonary Endarterectomy
JHLT: The Podcast
JHLT: The Podcast returns with an episode discussing the paper, “,” from the December issue of JHLT. They are joined by the first author, Camille Miard, MD, and senior author, François Stéphan, MD, PhD, both from the cardiothoracic intensive care unit at Hôpital Marie Lannelongue in Paris. The discussion explores: Whether antiphospholipid antibody titers could predict postoperative outcomes for CTEPH patients undergoing pulmonary endarterectomy (PEA) How APS patients differed from non-APS patients in the PEA cohort The changes in clinical practice at Marie Lannelongue...
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Episode 73: Lung Transplant in Patients with Suspicious Lung Lesions
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, “,” which appears in the December issue of JHLT. They are joined by the senior author, Stefan Schwarz, MD, PhD, of the Department of Thoracic Surgery at the Medical University of Vienna. The discussion explores: Methods used to assess the probability of malignancy in the patient cohort The limitations of common scanning methods in assessing this type of transplant patient What the study confirms or changes about standards in clinical practice For the latest studies from JHLT, visit , or, if...
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Episode 72: Impact of Donor-Specific Antibodies on Longitudinal Lung Function and BLAD
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors host a discussion on the paper, “.” They are joined by the first author, Muhtadi Alnababteh, MD, Assistant Professor at the University of Maryland and Staff Clinician at the National Institutes of Health, and senior author Michael Keller, MD, of the Pulmonary and Critical Care division at the University of Maryland. The discussion explores: Common characteristics of patients who developed donor-specific antibodies (DSA) Differences in outcomes depending on when DSA developed Associations between the development...
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Episode 71: Cardiogenic Shock Working Group: Patients on Impella 5.5 for more than 14 days
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite co-lead author Nir Uriel, MD, Director of Advanced Heart Failure and Cardiac Transplantation at New York Presbyterian Hospital and Professor of Medicine at Columbia University. Dr. Uriel joins to discuss the work of the Cardiogenic Shock Working Group (CSWG) and their recent paper, “.” The discussion explores: Why patients on longer duration of MCS had better survival but maintained similar rates of serious adverse events (SAEs) Why the study might show fewer SAEs than the literature historically shows How temporary...
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Episode 70: Passive Leg Raise and Occult HFpEF in Pulmonary Hypertension
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite author Dr. Ayumi Goda, from the Kyorin University Hospital in Tokyo, Japan, to discuss her team’s paper, “.” The discussion explores: How clinical observations led to the idea for a study on whether the passive leg raise could unmask occult HFpEF The potential diagnostic value of the passive leg raise in differing patient populations Age-specific cutoffs that may influence what kind of testing to use in clinical practice For the latest studies from JHLT, visit , or, if you’re an ISHLT member, access your Journal...
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Episode 69: Optimal Pre-Transplant Duration with HeartMate III LVADs
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Ahmet Bilgili, from the University of Florida’s Congenital Heart Center, and senior author Eric I. Jeng, MD, from the University of Florida’s MCS program. Bilgili and Dr. Jeng discuss their paper, “.” The discussion explores: Prior gaps in the literature regarding contemporary HM3 outcomes in relation to transplantation—and the study's potential influence on policy Which length of HM3 support influenced better post-transplant outcomes—and which ages were most influenced How these findings might...
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Episode 68: DCD lung procurement in the UK
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Luke Williams, a cardiothoracic surgery trainee at Royal Papworth Hospital, NHS Blood and Transplant Clinical Research Fellow, and a PhD student at Cambridge University in the UK. Luke discusses his paper, “.” The discussion explores: Requirements, regulations, and practices in the UK around DCD procurement and A-NRP How survival rates differ and what they might imply about primary graft dysfunction in DCD versus DBD Further work planned in the area in the UK and throughout Europe For the latest...
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Episode 67: Metabolic and transcriptomic insights into temperature-controlled donor heart transportation
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Gaurav Sharma, PhD, MBA, from the University of Texas Southwestern Medical Center in Dallas. Dr. Sharma discusses his paper, “.” The discussion explores: How donor hearts not offered or declined for transplantation responded in hypothermic preservation versus conventional static cold storage Potentially beneficial genetic signatures yielded by TCHP versus cold storage The surprising response of energy stores in the hearts to the different storage environments How multi-omic approaches could be applied to...
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Episode 65: Regional differences in primary graft dysfunction
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Joan Guzmán-Bofarull, and senior author, Marta Farrero, both of the Hospital Clinic de Barcelona in Spain. They join to discuss their paper, “.” The discussion explores: The international consortium on PGD, the composition of the study, and the practices of the included countries in the United States, Canada, and Europe Hypotheses on why the study shows better 30-day and 1-year outcomes in the United States Considerations transplant centers can take regarding recipient management and donor heart selection...
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Episode 65: Refining the grading of mild CAV
JHLT: The Podcast
On this episode of JHLT: The Podcast, the Digital Media Editors invite first author Nikil Prasad, MD, a cardiology fellow in the Columbia University Medical Center in New York, to discuss the paper, “.” The discussion explores: The study's subdivisions of CAV grade 1 into CAV 1a and CAV 1b, based on the degree of coronary stenosis Differing clinical information provided by different methods of CAV screening: reduced myocardial blood flow reserve vs angiographic grading Limitations in implementing PET-based CAV assessments at various centers, and how transplant programs can use combined...
info_outlineJHLT: The Podcast returns with an episode discussing the paper, “High Antiphospholipid Antibody Titers and Outcomes of Pulmonary Endarterectomy: A Single-Center Retrospective Observational Cohort Study,” from the December issue of JHLT.
They are joined by the first author, Camille Miard, MD, and senior author, François Stéphan, MD, PhD, both from the cardiothoracic intensive care unit at Hôpital Marie Lannelongue in Paris.
The discussion explores:
- Whether antiphospholipid antibody titers could predict postoperative outcomes for CTEPH patients undergoing pulmonary endarterectomy (PEA)
- How APS patients differed from non-APS patients in the PEA cohort
- The changes in clinical practice at Marie Lannelongue after the study's findings
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you’re an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
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