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#421: Trauma SCIENCE: How Hidden Stress Hijacks Your Health (Autoimmunity, Brain Inflammation, and Unlocking Resilience) | With Dr. Aimie Apigian

LONGEVITY with Nathalie Niddam

Release Date: 03/17/2026

#427: The Hidden Link Between Vision, Longevity & Anxiety | Spatial Empathy, Screens & the 20-20-20 Rule With Dr. Meenal Agarwal show art #427: The Hidden Link Between Vision, Longevity & Anxiety | Spatial Empathy, Screens & the 20-20-20 Rule With Dr. Meenal Agarwal

LONGEVITY with Nathalie Niddam

Today, I’m joined by the insightful , an eye doctor and passionate advocate for reimagining how we think about vision and brain health. In our conversation, Dr. Agarwal reveals the surprising ways our daily screen habits are shaping not just our eyesight, but also our emotional regulation, cognitive performance, and even the development of anxiety and ADHD-like symptoms. She opens up about her own journey—from an unexpected period of cognitive “off-ness” during a stint away from her clinical work, to pioneering a powerful perspective on “spatial awareness processing disorder.”...

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#426: The Invisible Price of Poor Sleep and How To Fix It, Tech Hacks That Save Marriages, and the Longevity Equation — With Melissa Urban show art #426: The Invisible Price of Poor Sleep and How To Fix It, Tech Hacks That Save Marriages, and the Longevity Equation — With Melissa Urban

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#425: Broccoli Power: The Secret Longevity Molecule (Fighting Toxins, Microplastics & Aging) | Sulforaphane Exposed With David Roberts & Dr. John Gildea show art #425: Broccoli Power: The Secret Longevity Molecule (Fighting Toxins, Microplastics & Aging) | Sulforaphane Exposed With David Roberts & Dr. John Gildea

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Today, I’m joined by , two passionate researchers whose work sits at the cutting edge of environmental health and longevity science. In this episode, we dive deep into the catalyst for developing a stabilized sulforaphane supplement—something born out of both necessity and relentless curiosity. David opens up about how environmental toxicity stopped being theoretical for him, and Dr. Gildea brings a wealth of clinical insight into why supporting our detox pathways could be a game-changer for chronic disease prevention. Offer: Get 25% off stabilized sulforaphane products for a limited time...

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#424: Part 2 - Follow Up To Dr. Bill Lawrence Episode: Answering More Of Your Bioregulator Questions With Nat Niddam & Erin Ryan show art #424: Part 2 - Follow Up To Dr. Bill Lawrence Episode: Answering More Of Your Bioregulator Questions With Nat Niddam & Erin Ryan

LONGEVITY with Nathalie Niddam

Today, I’m joined by Erin Ryan, my producer, for a special follow-up episode where we tackle your most pressing questions about bioregulators and peptides. After the wildly popular Bill Lawrence interview, the Longevity Podcast community sent in a wave of thoughtful queries—from cancer concerns to menopause, sourcing, and practical tips.   Books mentioned in this episode: (Great primer on bioregulators) Author: Dr. Marios Kyriazis   (Technical, science-heavy) Author: , ,     Episode Timestamps: Welcome and sponsor introduction ... 00:00:00 Autophagy and Primadene ......

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#423: Detox Pathways, Sensitive Systems, and the Truth About Chelation Therapy With ​​Dr. Nafysa Parpia show art #423: Detox Pathways, Sensitive Systems, and the Truth About Chelation Therapy With ​​Dr. Nafysa Parpia

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#422: Lessons from Centenarians: Immunity, Lifestyle, and Changing the Aging Game With Dr. Jeffrey Bland show art #422: Lessons from Centenarians: Immunity, Lifestyle, and Changing the Aging Game With Dr. Jeffrey Bland

LONGEVITY with Nathalie Niddam

Today, I’m joined by the legendary , widely known as the “father of functional medicine” and a true pioneer in the science of longevity and immune resilience. In this conversation, Dr. Jeffrey Bland opens up about his decades-long journey questioning the conventional medicine model, the personal moments that shaped his mission, and how his passion for asking the right questions ultimately led him to reshape the future of healthcare. Visit and get 15% off automatically at checkout.   Episode Timestamps: Focus on immune system aging ... 00:00:00 Questioning conventional medicine and...

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#421: Trauma SCIENCE: How Hidden Stress Hijacks Your Health (Autoimmunity, Brain Inflammation, and Unlocking Resilience) | With Dr. Aimie Apigian show art #421: Trauma SCIENCE: How Hidden Stress Hijacks Your Health (Autoimmunity, Brain Inflammation, and Unlocking Resilience) | With Dr. Aimie Apigian

LONGEVITY with Nathalie Niddam

Today, I’m joined by , an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine—where symptom management was the norm—to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity. The...

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#420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny show art #420: Spermidine UNLOCKED: Reverse Aging, Boost Immunity & Thrive After 40 With Leslie Kenny

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#419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana show art #419: A Mind-Blowing Mitochondria Episode— Mito Transplant, Rare Diseases & Biomarkers With Dr. Natalie Yivgi-Ohana

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#418: The Science of NAD+: Why Precursors & IVs Fail Without This Step With Courtney Van Bussum show art #418: The Science of NAD+: Why Precursors & IVs Fail Without This Step With Courtney Van Bussum

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More Episodes

Today, I’m joined by Dr. Aimie Apigian, an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine—where symptom management was the norm—to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity.

The 7-Day Somatic Healing for Stored Emotions - https://traumahealingaccelerated.mykajabi.com/a/2148170319/wdrhGYaY

21-Day Journey, a daily live session program that helps participants understand how much trauma their body may be holding - https://traumahealingaccelerated.mykajabi.com/a/2147704575/wdrhGYaY


Episode Timestamps:

Introduction, host’s mission, and episode theme ... 00:00:00

Science behind trauma, limits of traditional medicine, and autoimmune experiences ... 00:06:11

Attachment, symptom management, functional medicine, and healing journey ... 00:08:17

Mold exposure, state triggers, brain inflammation, and capacity blocks ... 00:14:22

Medical gaslighting, trauma validation, and biological capacity ... 00:18:25

Safety, resilience, and chronic survival state effects ... 00:19:32

Misconceptions about chronic stress—emergency brake and vagus nerve ... 00:22:27

Attachment patterns, autoimmunity, and shrinking world ... 00:28:47

Chronic survival loop, exhaustion, coping strategies, and shutdown ... 00:31:11

Moving to repair: phases of healing and gentle approaches ... 00:34:08

Somatic practices, art therapy, and different expressions of trauma ... 00:39:01

Shifts in sleep, digestion, anxiety, and felt safety ... 00:42:06

Tracking nervous system state: strategies and awareness ... 00:46:41

Therapy limitations: biology and somatic integration ... 00:48:42

Retraining vs. managing symptoms, stabilization, and healing ... 00:54:53

Capacity, resilience, lessons from centenarians, and longevity ... 01:00:06

Trauma’s impact on mitochondria, telomeres, and generational health ... 01:06:27

Gut microbiome and trauma: two-way connection ... 01:08:03

 

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Dr. Bill Lawrence Episode