#423: Detox Pathways, Sensitive Systems, and the Truth About Chelation Therapy With Dr. Nafysa Parpia
LONGEVITY with Nathalie Niddam
Release Date: 03/24/2026
LONGEVITY with Nathalie Niddam
Today, I’m joined by the insightful , a true leader in environmental and complex chronic illness medicine and the Director of Naturopathic Medicine at Gordon Medical. In our conversation, Dr. Parpia shares how her passion for deep, integrated healing brought her into the world of environmental toxins, hormone health, and the nuanced ways our bodies respond to the modern world. She opens up about her journey, the unique challenges women face—especially during menopause—and why so many aren’t finding answers in traditional medicine. Episode Timestamps: Welcome & episode goals...
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Today, I’m joined by the legendary , widely known as the “father of functional medicine” and a true pioneer in the science of longevity and immune resilience. In this conversation, Dr. Jeffrey Bland opens up about his decades-long journey questioning the conventional medicine model, the personal moments that shaped his mission, and how his passion for asking the right questions ultimately led him to reshape the future of healthcare. Visit and get 15% off automatically at checkout. Episode Timestamps: Focus on immune system aging ... 00:00:00 Questioning conventional medicine and...
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Today, I’m joined by , an innovative leader in the biology of trauma, whose work bridges the worlds of science, medicine, and lived experience. In our conversation, Dr. Apigian opens up about her journey from conventional medicine—where symptom management was the norm—to uncovering the physiological roots of trauma and the crucial role our nervous system plays in resilience and healing. She shares how her own health struggles, her work with adopted children, and a relentless curiosity led her to re-examine everything she thought she knew about stress, autoimmunity, and capacity. The...
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Today, I'm joined by the inspiring , Oxford-based longevity expert and a living example of turning adversity into vitality. After being told at 39 that she had lupus, rheumatoid arthritis, and just five years to live, Leslie defiantly forged a new path—reversing her diagnoses, restoring her thyroid health, and even welcoming a healthy baby girl at 43. Her story is a testament to the power of questioning the status quo, honoring the wisdom within our bodies, and refusing to accept decline as inevitable. Leslie has a generous offer for you, when you visit and use code BIONAT20 at...
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Today, I’m joined by the extraordinary , a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind—Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age. Episode Timestamps: Welcome to the Longevity Podcast and today's focus on mitochondria ... 00:00:00 Maternal inheritance and critical functions of mitochondria ... 00:05:56 Mitochondria as...
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Today, I’m joined by the insightful Courtney Van Bussum, a biomedical engineer and entrepreneur who has become a rising force in longevity science. Courtney shares how growing up in a family of healthcare innovators shaped her journey, and how she pivoted from startup life to tackling age-related challenges—especially when COVID brought her back to her roots and reignited her passion for cellular health. If you want to try Endotelio 1-MNA and save 10% and code NAT10 will be entered for you at checkout. Episode Timestamps: Welcome and introduction to Longevity Podcast ......
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Today, I’m joined by the innovative , a pediatrician whose passion for integrative and functional medicine has reshaped how we understand post-COVID health challenges. Dr. Keller opens up about her journey from conventional medicine to designing unique solutions for children and families, revealing how her care, presence, and determination to “solve the unsolvable” led to breakthroughs in treating mood changes, weight gain, and energy loss after COVID. Special Offer: If you go to and use code NatRocks at checkout, you’ll get a whopping 50% off of the Tryptophan Re-Genesis™...
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Today, I’m joined by the remarkable , whose work in the and vascular health space is changing the conversation around resilience and heart health for midlife women. Cathy dives into why cardiovascular disease is still the number one threat to women globally, and how the drop in estrogen during menopause impacts nitric oxide production—an overlooked factor that quietly influences everything from energy to cognition. Visit and use code NAT20 for 20% off. Episode Timestamps: Podcast welcome and cardiovascular focus ... 00:00:00 Introducing Cathy Eason, nitric oxide updates ......
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Today, I’m joined by Erin Ryan, my producer and long-time collaborator, for a special Q&A episode powered entirely by your questions. After our bioregulator deep dive with Dr. Bill Lawrence, the response was overwhelming—so many of you reached out with insightful queries about bioregulators, peptides, and the nuances between natural and synthetic options. Erin and I decided to tackle the most common themes, unpacking everything from organ versus system signaling to how bioregulators actually survive digestion. Nat’s favorite Bioregulators: and use code NAT15 for 15%...
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Today, I’m joined by the trailblazing , a cardiologist who reimagined heart health after years in elite academic medicine. In this episode, opens up about her journey from the traditional halls of Cornell and New York Presbyterian to creating truly personalized, preventive, and holistic programs for her patients—even when it meant leaving behind the medical mainstream. Episode Timestamps: Podcast intro and Dr. Druz’s background ... 00:00:00 The value of female perspectives in cardiology ... 00:04:11 Moving from traditional to integrative cardiology ... 00:13:17 Upsides of...
info_outlineToday, I’m joined by the insightful Dr. Nafysa Parpia, a true leader in environmental and complex chronic illness medicine and the Director of Naturopathic Medicine at Gordon Medical. In our conversation, Dr. Parpia shares how her passion for deep, integrated healing brought her into the world of environmental toxins, hormone health, and the nuanced ways our bodies respond to the modern world. She opens up about her journey, the unique challenges women face—especially during menopause—and why so many aren’t finding answers in traditional medicine.
Episode Timestamps:
Welcome & episode goals ... 00:00:00
Environmental toxins and complex illness ... 00:01:17
Rise of chronic illnesses; environmental triggers ... 00:07:26
Lead, bone loss, and menopause ... 00:10:03
Sources of lead exposure today ... 00:12:03
Chelation therapy: what, when, and how ... 00:14:26
Opening detox pathways: herbs and bioregulators ... 00:17:17
Menopause, toxic burden, and immune shifts ... 00:20:49
CDC data: multiple toxins and cumulative risk ... 00:23:02
Genetics, nutrition, and susceptibility ... 00:28:12
Personalized medicine & system constraints ... 00:30:03
Heavy metals, inflammation, and hormone effects ... 00:35:35
Peptide and bioregulator therapy: sequencing matters ... 00:41:12
Testing mistakes: over- and under-testing ... 00:57:41
Preparing for detox: the Pretox approach ... 01:02:58
Sensitivity to binders and protocol adjustments ... 01:16:50
Plasmapheresis (TPE): science and application ... 01:19:19
Optimizing menopause care and women’s self-sovereignty ... 01:25:28
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