MTHFR Gene with Elyse Dworin

Could a common gene variant be quietly clogging the system for you or your child?

In this episode of Complicated Kids, I sit down with holistic academic coach Elyse Dworin to talk about the MTHFR gene: what it is, what it does, and why it matters for neurodivergent kids and their parents. Elyse explains, in plain language, how this gene helps the body process folate, manage toxins, and regulate inflammation, and what can happen when a variant plus a modern “enriched” diet start to overload the system.

We get into her personal story of brain fog, gut issues, anxiety, and years of “IBS” labels before testing finally revealed toxic levels of heavy metals, sky-high folic acid, and an MTHFR variant. From there, we talk about what families can actually do: shifting away from processed and fortified foods, choosing methylated vitamins, supporting detox with a knowledgeable provider, and paying attention to how our bodies respond.

We also zoom out to the bigger picture: how food, sleep, movement, medications, environment, and nervous system sensitivity all weave together. And because this is Complicated Kids, we talk about what this looks like in real life with real kids: the Halloween candy, the Goldfish, the push-pull of autonomy, and how to work toward balance without turning food into a power struggle.

Key Takeaways

• The MTHFR gene is involved in repairing DNA, managing homocysteine, recycling antioxidants, and helping the body process toxins and allergens.
• There are common MTHFR variants. When present, especially alongside high folic acid intake, they can contribute to issues like brain fog, anxiety, ADHD-like symptoms, and mood challenges.
• Folic acid (synthetic) is not the same as folate (naturally found in leafy greens), and people with MTHFR variants may not process folic acid well.
• “Enriched” or “fortified” on ingredient labels usually means folic acid has been added, common in many flours, cereals, and boxed foods.
• Over time, unprocessed folic acid and toxins can “clog the drain,” leading to overload in the system rather than smooth detox and regulation.
• Testing with a holistic or functional provider can help identify MTHFR variants, heavy metal loads, and vitamin/mineral imbalances.
• Detox protocols should always be done under medical supervision, because releasing too many stored toxins at once can overwhelm the body.
• Practical support often includes shifting toward whole foods, adding leafy greens, and using methylated B vitamins instead of standard multivitamins.
• Behavior is communication, sometimes emotional, sometimes physical, and it can be a clue that something in the body is not working well.
• With kids, especially tweens and teens, education, moderation, and collaboration usually work better than restriction and force when it comes to food.
• Learning to tune into your own body (and helping kids tune into theirs) is a powerful lifelong skill that supports focus, mood, and resilience.

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About Elyse Dworin

Elyse Dworin is the founder of Elevated Learning Solutions, a holistic academic support practice that helps students thrive by understanding not only how they learn best, but also what supports their bodies and brains to function at their best. Drawing on her strong background in math and dual degrees in Special Education and Exceptional Learners, she blends academic instruction with metacognition, executive functioning support, study skills, and social-emotional strategies. Elyse also coaches parents to better understand their child’s learning profile and build realistic, compassionate supports at home. She lives in Germantown with her husband and two young children.

About Your Host, Gabriele Nicolet

I’m Gabriele Nicolet, toddler whisperer, speech therapist, parenting life coach, and host of Complicated Kids. Each week, I share practical, relationship-based strategies for raising kids with big feelings, big needs, and beautifully different brains. My goal is to help families move from surviving to thriving by building connection, confidence, and clarity at home.

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